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Omschrijving: The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Catalogus nummer: BOSSBS-2684R-HRP
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system, causing a hyperpolarization of the membrane through the opening of a Cl- channel associated with the GABAA-Receptor (GABAA-R) subtype. GABAA-Rs are important therapeutic targets for a range of sedative, anxiolytic, and hypnotic agents and are implicated in several diseases including epilepsy, anxiety, depression, and substance abuse. The GABAA-R is a multimeric subunit complex. To date six alphas, four betas and four gammas, plus alternative splicing variants of some of these subunits, have been identified. Injection in oocytes or mammalian cell lines of cRNA coding for alpha and beta subunits results in the expression of functional GABAA-Rs sensitive to GABA. However, coexpression of a gamma subunit is required for benzodiazepine modulation. The various effects of the benzodiazepines in brain may also be mediated via different alpha subunits of the receptor. Lastly, phosphorylation of beta subunits of the receptor has been shown to modulate GABAA-R function.
Catalogus nummer: PRSIXPS-2011
UOM: 1 * 100 µl
Leverancier: ProSci Inc.


Omschrijving: Fetal ear, skin, and tongue and human cell lines. Highly up-regulated in psoriatic epidermis. Also highly expressed in the urine of bladder squamous cell carcinoma (SCC) bearing patients.
Catalogus nummer: BOSSBS-6575R-A488
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Involved in the conversion of lanosterol to cholesterol.Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes.
Catalogus nummer: BOSSBS-4221R-CY5.5
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Economy line 2.0 is een eenvoudige laboratoriumstoel die toch voldoet aan alle eisen die een laboratorium met zich meebrengt. De stoel is ergonomisch, robuust, gemakkelijk schoon te maken, intuïtief in gebruik en heeft een uitstekende prijs-prestatieverhouding.
Catalogus nummer: 132-1407
UOM: 1 * 1 ST
Leverancier: VWR Collection

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Omschrijving: Possesses microtubule stabilizing properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53-dependent manner.Tissue specificity: Abundant in testis, thymus, and in tumor derived cell lines, while barely detectable in liver, prostate, and kidney.
Catalogus nummer: BOSSBS-7745R-CY7
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Fetal ear, skin, and tongue and human cell lines. Highly up-regulated in psoriatic epidermis. Also highly expressed in the urine of bladder squamous cell carcinoma (SCC) bearing patients.
Catalogus nummer: BOSSBS-6575R-A647
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Fetal ear, skin, and tongue and human cell lines. Highly up-regulated in psoriatic epidermis. Also highly expressed in the urine of bladder squamous cell carcinoma (SCC) bearing patients.
Catalogus nummer: BOSSBS-6238R-A647
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Fetal ear, skin, and tongue and human cell lines. Highly up-regulated in psoriatic epidermis. Also highly expressed in the urine of bladder squamous cell carcinoma (SCC) bearing patients.
Catalogus nummer: BOSSBS-6238R-A488
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Involved in the conversion of lanosterol to cholesterol.Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes.
Catalogus nummer: BOSSBS-4221R-HRP
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Involved in the conversion of lanosterol to cholesterol.Expressed in adult heart, brain, pancreas, lung, liver, skeletal muscle, kidney, ovary, prostate, and testis, but not detected in placenta, spleen, thymus, small intestine, colon (mucosal lining), or peripheral blood leukocytes.
Catalogus nummer: BOSSBS-4221R-FITC
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Detected at the highest levels in peripheral blood leukocytes and breast cancer cell lines. Found in leukocytes of the myeloid lineage, with the strongest expression observed in granulocytes and no detectable expression in lymphocytes. Expressed in thymic epithelial cells and fibroblasts.Belongs to the SECTM family.
Catalogus nummer: BOSSBS-10153R-A750
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Possesses microtubule stabilising properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53-dependent manner.Tissue specificity: Abundant in testis, thymus, and in tumor derived cell lines, while barely detectable in liver, prostate, and kidney.
Catalogus nummer: BOSSBS-7745R-A750
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Possesses microtubule stabilising properties. Involved in regulating aneuploidy, cell cycling, and cell death in a p53/TP53-dependent manner.Tissue specificity: Abundant in testis, thymus, and in tumor derived cell lines, while barely detectable in liver, prostate, and kidney.
Catalogus nummer: BOSSBS-7745R-A680
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodelling. Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth.
Catalogus nummer: BOSSBS-0823R-A750
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling. Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth.
Catalogus nummer: BOSSBS-0823R-A350
UOM: 1 * 100 µl
Leverancier: Bioss