Anti-HCAR2 Rabbit Polyclonal Antibody

Leverancier: ProSci Inc.
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56-577
PRSI56-577EA 620 EUR
PRSI56-577
Anti-HCAR2 Rabbit Polyclonal Antibody
Antilichamen
NIACR1 acts as a high affinity receptor for both nicotinic acid (also known as niacin) and (D)-beta-hydroxybutyrate and mediates increased adiponectin secretion and decreased lipolysis through G(i)-protein-mediated inhibition of adenylyl cyclase. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet. Mediates nicotinic acid-induced apoptosis in mature neutrophils. Receptor activation by nicotinic acid results in reduced cAMP levels which may affect activity of cAMP-dependent protein kinase A and phosphorylation of target proteins,More Product Information
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Specificaties

antigeen symbool HCAR2
Environmentally Preferable
Type antilichaam Primair,Hydroxycarboxylic acid receptor 2
Type antilichaam Primair,Hydroxycarboxylic acid receptor 2
Clonality Polyklonaal
Conjugatie Onconjugeerd
Reactivity Human
Host Rabbit
Gen-ID Q8TDS4
Isotype
Western blot Yes
Modification None
Epitoop Amino acid range = 200-228
Immunogeen This NIACR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 200-228 amino acids from the Central region of human NIACR1
Formulier Liquid
Moleculair gewicht 42 kDa
Purification This antibody is purified through a protein A column, followed by peptide affinity purification
Concentratie 0,5 mg/ml
Opslagbuffer Supplied in PBS with 0,09% (W/V) sodium azide
Opslagtemperatuur Store at 4 °C for three months and –20 °C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Shipping temperature 4 °C

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