Human recombinant QAPRTase (from E. coli)

Leverancier: ProSci Inc.
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91-237
PRSI91-237EA 982 EUR
PRSI91-237
Human recombinant QAPRTase (from E. coli)
Enzymen

Nicotinate-Nucleotide Pyrophosphorylase (QPRT) belongs to the nadC/modD family. QPRT plays an improtant role in catabolism of quinolinate which acts as a potent endogenous exitotoxin to neurons. In addition, QPRT serves as an an intermediate in the Tryptophan-Nicotinamide Adenine Dinucleotide pathway. QPRT participates in some pathways including Cofactor biosynthesis, NAD(+) biosynthesis and the Nicotinate D-Ribonucleotide from Quinolinate. In addition, QPRT is involved in the catabolism of Quinolinic Acid (QA). The activity toward QA is slightly repressed by phosphoribosylpyrophosphate (PRPP) in both a competitive and a non-competitive manner.


Fusion-Tag: N-6 His tag


This recombinant protein can be used for biological assays. For research use only.

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