Human recombinant PPIase (from E. coli)

Leverancier: ProSci Inc.
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91-271
PRSI91-271EA 884 EUR
PRSI91-271
Human recombinant PPIase (from E. coli)
Enzymen

Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family. PPIases can accelerate the folding of proteins and catalyze the cis-trans isomerisaion of proline imidic peptide bonds in oligopeptides. PPIase is a ubiquitous protein and has highly expression in heart ,skeletal and muscle. PPIase contains a PPIase cyclophilin-type domain and four Cyclosporin A binding regions. PPIase might play an important role in proliferation of cancer cells through modulation of phosphorylation of stathmin. It is suggested that PPIase can act as as a novel molecular target for colon-cancer therapy.


Fusion-Tag: N-6 His tag


This recombinant protein can be used for biological assays. For research use only.

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Specificaties

Enzym naam PPIase
Environmentally Preferable
Enzym type Recombinant
Bron E. coli
Species Human
Sequentie Met1-Gly166
Moleculair gewicht 20.4 kD
Zuiverheid >95% as determined by reducing SDS-PAGE
Storage conditions Store at −20 °C, stable for 6 months after receipt. Please minimize freeze−thaw cycles.
Formulering Supplied as a 0.2 µm filtered solution of 20 mM TrisHCl, pH 8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Tested applications Bioassay
Tag sequence N-6 His tag

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