U heeft gezocht op: β-Nicotinamide adenine dinucleotid, oxidised form (NAD, oxidized form)


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Leverancier: Merck
Omschrijving: β-Nicotinamide adenine dinucleotid, oxidised form (NAD, oxidised form), Millipore®
Leverancier: PanReac AppliChem
Omschrijving: β-Nicotinamide adenine dinucleotid, oxidised form (NAD, oxidised form)
Leverancier: Thermo Fisher Scientific
Omschrijving: β-Nicotinamide adenine dinucleotid, oxidised form (NAD, oxidised form) 97%
Leverancier: Merck Millipore (Calbiochem‎)
Omschrijving: β-Nicotinamide adenine dinucleotid, oxidised form (NAD, oxidised form), Millipore®
Leverancier: MP Biomedicals
Omschrijving: Storage: -20°C, desiccate
This is an ultrapure NAD, chromatographically purified to remove trace inhibitors.
β-NAD, a pyridine nucleotide and biologically active form of nicotinic acid, is a coenzyme necessary for the catalytic reaction of certain enzymes. It occurs in living cells primarily in the oxidized state. Serves as a coenzyme of the dehydrogenases, especially in the dehydrogenation of primary and secondary alcohols. NAD usually acts as a hydrogen acceptor, forming NADH which then serves as a hydrogen donor in the respiratory chain.
Many metabolites and enzymes of biological interest are present in tissues at low concentrations. With the use of β-NAD as a catalyst intermediate and several enzymes in a multistep system, known as enzyme cycling, much greater sensitivity for detection of these components is achieved. The reduced form, β-NADH, is fluorescent whereas β-NAD is not. This difference in fluorescence provides a sensitive fluorescent measurement of the oxidized or reduced pyridine nucleotides at concentrations down to 10-7 M.
Electron acceptor. β-NAD is a carrier for hydride ion, forming b-NADH. Hydride ion is enzymatically removed from a substrate molecule by the action of dehydrogenases such as malic dehydrogenase and lactic dehydrogenase. Such enzymes catalyze the reversible transfer of a hydride ion from malate or lactate to b-NAD to form the reduced product, b-NADH. Unlike b-NAD which has no absorbance at 340 nm, b-NADH absorbs at 340 nm (EmM = 6.22). The increase in absorbance at 340 nm with the formation of b-NADH is the basis for measurement of activity of many enzymes.

Leverancier: MP Biomedicals
Omschrijving: Major electron acceptor molecule in biological oxidations. Acts as a coenzyme for hydride-transfer enzymes and a substrate for NAD(+)-consuming enzymes, which include ADP-ribose transferases, poly(ADP-ribose) polymerases, cADP-ribose synthases and sirtuins. Recently reported to be a P2Y11 agonist.

Leverancier: MP Biomedicals
Omschrijving: This grade of NAD is intended for applications where maximum reagent purity is not critical. Well suited for use on most automatic analysers.

Leverancier: Serva
Omschrijving: β-Nicotinamide adenine dinucleotid, oxidised form (NAD, oxidised form)

Leverancier: Roth Carl
Omschrijving: β-Nicotinamide adenine dinucleotid, oxidised form (NAD, oxidised form)

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
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