U heeft gezocht op: Rapamycin

Leverancier: ENZO LIFE SCIENCES

Omschrijving: Macrocyclic-triene antibiotic possessing potent immunosuppressant activity. It forms a complex with FKBP12 that binds to an effector, thus inhibiting IL-2 and other growth promoting lymphokines. The effectors were identified as FRAP (FKBP12 rapamycin-associated protein) and RAFT1 (rapamycin and KFBP12 target). rapamycin/FKBP complex does not inhibit FRAP PI 4-kinase activity, but does inhibit FRAP autophosphorylation. rapamycin induces inhibition of p70^s6k, p33^cdk2 and p34^cdc2. Selectively blocks signaling leading to the activation of p70/85 S6 kinase. Enhances apoptosis. Activator of autophagy both<i> in vitro</i> and <i>in vivo</i>.

Catalogus nummer: (TCIAR0097-25MG)

Leverancier: TCI

Omschrijving: Rapamycin ≥98.0% (by HPLC)

UOM: 1 * 25 mg

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Leverancier: Apollo Scientific

Omschrijving: Macrocyclic triene antibiotic.

Leverancier: Thermo Fisher Scientific

Omschrijving: Rapamycin ≥99%

MSDS Certificaten

Leverancier: MP Biomedicals

Omschrijving: Rapamycin binds to and inhibits the molecular target of Rapamycin (mTOR). It forms a complex with FKBP12 that binds to and inhibits the molecular target of Rapamycin (mTOR). Rapamycin is a potent immunosuppressant and has anticancer activity.