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Omschrijving: CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. Amember of the chordin family of proteins, it contains a signal peptide andthree CR (cysteine-rich repeat) domains. When expressed as a recombinantprotein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterized as a novel protein exclusively expressed in breast, lung, and colon tumors.
Catalogus nummer: BOSSBS-3860R-HRP
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Lanthanum(III) chloride, ultra dry ≥99.99% (REO, rare earth oxide basis)
Catalogus nummer: 35731.14
UOM: 1 * 25 g
Leverancier: Thermo Fisher Scientific

Omschrijving: May negatively regulate cell cycle progression. May act at least in part via inhibition of the cyclin-D1/CDK4 complex, thereby preventing phosphorylation of RB1 and blocking E2F-dependent transcription.Tissue specificity: Ubiquitously expressed. Expression is down-regulated in a variety of tumor types including breast, colon, prostate and rectal tumors, and is up-regulated in certain hepatic carcinomas.
Catalogus nummer: BOSSBS-7885R-A647
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: The exosome is a multi-protein complex composed of several highly conserved subunits, some of which are 3? to 5? exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich elements (AREs) in their untranslated 3? regions. DIS3, also known as RRP44, is a 958 amino acid protein that localises to both the cytoplasm and the nucleus and contains one PINc domain. Widely expressed with highest expression in testis, DIS3 functions as a component of the exosome exoribonuclease complex and is required for processing of 7S pre-RNA into a mature nuclear complex and, ultimately, for proper mitotic progression. Abnormal expression levels of DIS3 may be associated with colon cancer, suggesting a role for DIS3 in tumorigenesis. Multiple isoforms of DIS3 exist due to alternative splicing events.
Catalogus nummer: BOSSBS-9052R-A680
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Ytterbium(III) chloride hydrate ≥99.9% (REO, rare earth oxide basis), REacton®
Catalogus nummer: 11193.18
UOM: 1 * 50 g
Leverancier: Thermo Fisher Scientific

Omschrijving: Ruthenium(III) chloride hydrate 97%
Catalogus nummer: APOSIN3062-25G
UOM: 1 * 25 g
Leverancier: Apollo Scientific


Omschrijving: Lanthaan(III)chloride heptahydraat ACS
Catalogus nummer: APOSIN2120-100G
UOM: 1 * 100 g
Leverancier: Apollo Scientific


Omschrijving: Antimoontrichloride for synthesis, Sigma-Aldrich®
Catalogus nummer: 8.14656.0250
UOM: 1 * 250 g
Leverancier: Merck

MSDS


Omschrijving: Chloropentaammineiridium(III) chloride (≥49,6% Ir) ≥99.9% (metals basis)
Catalogus nummer: 41006.03
UOM: 1 * 1 g
Leverancier: Thermo Fisher Scientific

Omschrijving: CHRDL2 is a novel chordin like protein that can act as a BMP antagonist. Amember of the chordin family of proteins, it contains a signal peptide andthree CR (cysteine-rich repeat) domains. When expressed as a recombinantprotein it is secreted and binds to activin A, but not to BMP-2, -4, -6. Differential expression has been detected in developing chondrocytes, myoblasts, osteoblasts, and osteoarthritic joints. Complex alternative splicing of CHRDL2 potentially results in distinct isoforms that differ at their C termini, in the expression of signal peptide, and in the content of CR domains. CHRDL2 was originally characterized as a novel protein exclusively expressed in breast, lung, and colon tumors.
Catalogus nummer: BOSSBS-3860R-FITC
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Gallium(III) chloride, ultra dry ≥99.999% (metals basis)
Catalogus nummer: 43879.06
UOM: 1 * 5 g
Leverancier: Thermo Fisher Scientific

Omschrijving: Europium(III) chloride hexahydrate 99.9% (trace metals basis) -10 mesh
Catalogus nummer: ACRO199600050
UOM: 1 * 5 g
Leverancier: Thermo Fisher Scientific

MSDS


Omschrijving: Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1, PU1, ATF2, UBF, Elf1 and cAbl. This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks). Rb is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus 16E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the Rb gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
Catalogus nummer: BOSSBS-5667R-CY3
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1, PU1, ATF2, UBF, Elf1 and cAbl. This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks). Rb is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus 16E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the Rb gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
Catalogus nummer: BOSSBS-5667R-CY7
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1, PU1, ATF2, UBF, Elf1 and cAbl. This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks). Rb is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus 16E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the Rb gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
Catalogus nummer: BOSSBS-5666R-A488
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1, PU1, ATF2, UBF, Elf1 and cAbl. This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks). Rb is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus 16E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the Rb gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.
Catalogus nummer: BOSSBS-5666R-A350
UOM: 1 * 100 µl
Leverancier: Bioss


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