Anti-CD4 Rat Monoclonal Antibody (FITC (Fluorescein)) [clone: RM4-5]

Leverancier: Tonbo Biosciences
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35-0042-U500 35-0042-U100 35-0042-U025
35-0042-U500EA 104 EUR
35-0042-U500 35-0042-U100 35-0042-U025
Anti-CD4 Rat Monoclonal Antibody (FITC (Fluorescein)) [clone: RM4-5]
Antilichamen
The RM4-5 antibody reacts with mouse CD4, a 55 kDa protein which acts as a co-receptor for the T cell receptor (TCR) in its interaction with MHC Class II molecules on antigen-presenting cells. The extracellular domain of CD4 binds to the beta2-domain of MHC Class II, while its cytoplasmic tail provides a binding site for the tyrosine kinase lck, facilitating the signaling cascade that initiates T cell activation. CD4 is typically expressed on thymocytes, certain mature T cell populations such as Th17 and T regulatory (Treg) cells, as well as on dendritic cells.

The RM4-5 antibody isMore Product Information
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Specificaties

antigeen symbool CD4
Environmentally Preferable
Type antilichaam CD4 molecule,Primair
Antigeen synoniemen L3T4|p55|CD4mut|Ly-4|W3/25
Type antilichaam CD4 molecule,Primair
Clonality Monoklonaal
Conjugatie FITC (Fluoresceïne-isothiocyanaat)
Clone RM4-5
Reactivity Mouse
Host Rat
Gen-ID 12504
Isotype IgG2a kappa
ImmunoChemie Yes
ImmunoNeerslag Yes
ImmunoFluorescentie Yes
Flowcytometrie Yes
Kruisadsorptie none
Opslagtemperatuur Cool
Shipping temperature Ice

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