Anti-HLA-DRB1 Mouse Monoclonal Antibody (Biotin) [clone: L243]

Leverancier: Biotium
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BNCB0458-500 BNCB0458-100
BNCB0458-500EA 560 EUR
BNCB0458-500 BNCB0458-100
Anti-HLA-DRB1 Mouse Monoclonal Antibody (Biotin) [clone: L243]
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This MAb reacts with the HLA-DRB1 antigen, a member of MHC class II molecules. It does not cross react with HLA-DP and HLA-DQ. It binds a conformational epitope on HLA-DR, which depends on the correct folding of the α/β heterodimer. This MAb has been reported to block mixed lymphocyte reactions. The L243 antibody recognizes a different epitope than the LN3 monoclonal antibody, and these antibodies do not cross-block binding to each other's respective epitopes. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kD alpha (heavy) chain and a 28kD beta (light) chain. It isMore Product Information
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