Anti-TP53 Mouse Monoclonal Antibody (CF488A) [clone: DO-7]

Leverancier: Biotium
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BNC880513-500 BNC880513-100
BNC880513-500EA 560 EUR
BNC880513-500 BNC880513-100
Anti-TP53 Mouse Monoclonal Antibody (CF488A) [clone: DO-7]
Antilichamen
Recognizes a 53 kDa protein, which is identified as p53 suppressor gene product. It reacts with the mutant as well as the wild form of p53. Its epitope maps within the N-terminus (aa 37-45) of p53. Monoclonal antibody PAb1801 does not block the binding of DO-7 MAb to p53 in an ELISA test. p53 is a tumor suppressor gene expressed in a wide variety of tissue types and is involved in regulating cell growth, replication, and apoptosis. It binds to MDM2, SV40 T antigen and human papilloma virus E6 protein. Positive nuclear staining with p53 antibody has been reported to be a negative prognosticMore Product Information
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Specificaties

antigeen symbool TP53
Type antilichaam Primair,p53
Environmentally Preferable
Antigeen synoniemen Transformation Related Protein 53 (TRP53)|Tumor Protein p53|BCC7|Cellular Tumor Antigen p53|Tumor Suppressor p53|TP53|LFS1|Antigen NY-CO-13
Type antilichaam Primair,p53
Clonality Monoklonaal
Conjugatie CF® 488A
Clone Clone DO-7
Reactivity Monkey,Human,Bovine
Host Mouse
Gen-ID 654481
Isotype IgG2b kappa
Western blot Yes
ImmunoChemie Yes
ImmunoFluorescentie Yes
Concentratie 0,1 mg/ml
Opslagbuffer PBS/0,1% BSA/0,05% azide

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