Anti-CDKN1B Mouse Monoclonal Antibody (CF405S) [clone: SX53G8]

Leverancier: Biotium
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BNC040669-500 BNC040669-100
BNC040669-500EA 560 EUR
BNC040669-500 BNC040669-100
Anti-CDKN1B Mouse Monoclonal Antibody (CF405S) [clone: SX53G8]
Antilichamen
This MAb recognizes a 27 kDa protein, identified as the p27Kip1, a cell cycle regulatory mitotic inhibitor. It is highly specific and shows no cross-reaction with other related mitotic inhibitors. In Western blotting of cell lysates from 7 human breast cancer cell lines (ZR75-1, ZR75-30, MCF-7, MDAMB453, T47D, CAL51, 734B), the antibody labels a single band corresponding to p27Kip1. It functions as a negative regulator of G1 progression and has been proposed to function as a possible mediator of TGF- induced G1 arrest. p27Kip1 is a candidate tumor suppressor gene. Reportedly, low p27More Product Information
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Specificaties

antigeen symbool CDKN1B
Type antilichaam Primair,Cyclin-dependent kinase inhibitor 1B
Environmentally Preferable
Antigeen synoniemen CDKN1B|CDKN4|KIP1|Cyclin-dependent kinase inhibitor p27 Kip1|MEN1B|Cyclin Dependent Kinase Inhibitor 1B|MEN4
Type antilichaam Primair,Cyclin-dependent kinase inhibitor 1B
Clonality Monoklonaal
Conjugatie CF® 405S
Clone Clone SX53G8
Reactivity Monkey,Human,Rat,Mouse
Host Mouse
Gen-ID 238990
Isotype IgGs
Western blot Yes
ImmunoChemie Yes
ImmunoFluorescentie Yes
Concentratie 0,1 mg/ml
Opslagbuffer PBS/0,1% BSA/0,05% azide

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