Anti-TYR Mouse Monoclonal Antibody (CF568) [clone: T311 OCA1/812]

Leverancier: Biotium
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BNC680908-500 BNC680908-100
BNC680908-500EA 560 EUR
BNC680908-500 BNC680908-100
Anti-TYR Mouse Monoclonal Antibody (CF568) [clone: T311 OCA1/812]
Antilichamen
Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cellMore Product Information
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Specificaties

antigeen symbool TYR
Type antilichaam Primair,Tyrosinase
Environmentally Preferable
Antigeen synoniemen Tumor rejection antigen AB|ATN|CMM8|SHEP3|Oculocutaneous albinism IA|Monophenol monooxygenase|OCA1A|OCA1|TYR|LB24-AB|SK29-AB
Type antilichaam Primair,Tyrosinase
Clonality Monoklonaal
Conjugatie CF® 568
Clone Clone T311 OCA1/812
Reactivity Human
Host Mouse
Gen-ID 503555
Isotype IgG
ImmunoChemie Yes
ImmunoFluorescentie Yes
Concentratie 0,1 mg/ml
Opslagbuffer PBS/0,1% BSA/0,05% azide

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