Anti-FCGR3A Mouse Monoclonal Antibody (CF640R) [clone: HuNK2]

Leverancier: Biotium
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BNC400928-500 BNC400928-100
BNC400928-500EA 560 EUR
BNC400928-500 BNC400928-100
Anti-FCGR3A Mouse Monoclonal Antibody (CF640R) [clone: HuNK2]
Antilichamen
Recognizes a protein of 50-65 kDa, identified as CD16 (Workshop IV; Code N39 ) (also known low affinity Fc receptor III for IgG (FcRIII) or Leu 11). CD16 exists as a polypepetide-anchored from (FCRIIIA or CD16A) on human natural killer (NK) cells and monocytes/ macrophages and as a glycosylphosphatidylinositol (GPI)-anchored form (FcRIIIB or CD16B) on neutrophils. CD16B is polymorphic and the two alleles are termed NA1 and NA2.3 CD16 plays a role in signal transduction, NK cell activation and antibody-dependent cellular cytotoxicity. This MAb has been showed to inhibit the binding of immuneMore Product Information
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