Anti-UACA Mouse Monoclonal Antibody (CF594) [clone: AE-5]

Leverancier: Biotium
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BNC940956-500 BNC940956-100
BNC940956-500EA 560 EUR
BNC940956-500 BNC940956-100
Anti-UACA Mouse Monoclonal Antibody (CF594) [clone: AE-5]
Antilichamen
UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.

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Specificaties

antigeen symbool UACA
Type antilichaam Primair,UACA / Nucling
Environmentally Preferable
Antigeen synoniemen Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA)|NUCLING|Nuclear membrane binding protein
Type antilichaam Primair,UACA / Nucling
Clonality Monoklonaal
Conjugatie CF® 594
Clone Clone AE-5
Reactivity Human,Mouse
Host Mouse
Gen-ID 108049
Isotype IgG1 kappa
Western blot Yes
ImmunoFluorescentie Yes
Concentratie 0,1 mg/ml
Opslagbuffer PBS/0,1% BSA/0,05% azide

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