Furin convertase inhibitor (chloromethylketone)

Leverancier: ENZO LIFE SCIENCES
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ALX260022M001 ALX260022M005
ENZOALX260022M001EA 253 EUR
ENZOALX260022M001 ENZOALX260022M005
Furin convertase inhibitor (chloromethylketone)
Eiwitten en peptiden

Highly specific, potent, irreversible, and cell-permeable competitive inhibitor of proprotein convertases: furin/SPC1 (Ki~1 nM), SPC2/PC2 (Ki=0.36nM), SPC3/PC1/PC3(Ki= 2,0nM), SPC4/PACE4 (Ki=3,6 nM), SPC6/PC5/PC6, and SPC7/LPC/PC7/PC8 (Ki=0,12 nM). Because furin activates viral glycoproteins, this inhibitor is a useful antiviral agent. In addition, it inhibits furin-dependent pro-MMP-2 activation in various cell lines, including U87 and HT1080 cells. Typical concentration range used in tissue culture is 25 to100 µm.


  • Highly specific, potent, irreversible, and cell-permeable competitive inhibitor of proprotein convertases.


White to off-white powder.


Soluble in DMSO, methanol or water.

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