2,3',4,5'-Tetramethoxystilbene ≥98%
Leverancier: Cayman ChemicalTotal Ratings: 0
Avg. Ratings: 0.0 out of 5
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Waarschuwing
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TMS is a potent and selective inhibitor of CYP1B1, with an IC50 of 6 nM.
CYP1B1 is mainly an extrahepatic enzyme which oxidatively metabolises both endogenous (steroids; eicosanoids) and exogenous xenobiotics such aspolyaromatic hydrocarbons.
It is 50-fold selective for the inhibition of CYP1B1 versus CYP1A1, making it a useful tool to differentiate between various CYP450 families. In cultured human colon cancer cells, TMS induces apoptosis and inhibits cell growth with an IC50 of 0.8 µg/ml.
Formule:
C₁₈H₂₀O₄ Smeltpunt: -99 °C Bewaar temperatuur: Vriezer |
MDL Nummer:
MFCD03428621 CAS nummer: 24144-92-1 |
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