Human Recombinant Follistatin (from E. coli)

Leverancier: Shenandoah Biotechnology
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100-41-100UG 100-41-1MG 100-41-20UG 100-41-500UG 100-41-5UG
SHBT100-41-100UGEA 699 EUR
SHBT100-41-100UG SHBT100-41-1MG SHBT100-41-20UG SHBT100-41-500UG SHBT100-41-5UG
Human Recombinant Follistatin (from E. coli)
Eiwitten en peptiden

Follistatin is an autocrine, activin-binding protein that is ubiquitously expressed with highest expression levels being in the ovary and skin. Follistatin negatively regulates the signaling of transforming growth factor beta (TGF-β) family members, such as activin, bone morphogenetic proteins (BMPs), myostatin, growth differentiation factor 11 (GDF-11), and TGF-β1. Follistatin functions as an antagonist by binding TGF-β family members to block interaction with their signaling receptors. Follistatin also inhibits the secretion of follicle-stimulating hormone (FSH) from the anterior pituitary.


  • High quality
  • Low endotoxin
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Opgelet: For research use only.

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Specificaties

Protein/peptide name Follistatin
Environmentally Preferable
Protein synonyms FS|activin-binding protein|FSH-suppressing protein (FSP)
Protein/peptide type Recombinant
Protein function Cytokine
Species Human
Bron E. coli
Conjugatie Onconjugeerd
Gen-ID P19883
Sequentie mgNCWLRQAK NGRCQVLYKT ELSKEECCST GRLSTSWTEE DVNDNTLFKW MIFNGGAPNC IPCKETCENV DCGPGKKCRMNKKNKPRCVC APDCSNITWK GPVCGLDGKT YRNECALLKA RCKEQPELEV QYQGRCKKTC RDVFCPGSST CVVDQTNNAY CVTCNRICPEPASSEQYLCG NDGVTYSSAC HLRKATCLLG RSIGLAYEGK CIKAKSCEDI QCTGGKKCLW DFKVGRGRCS LCDELCPDSK SDEPVCASDNATYASECAMK EAACSSGVLL EVKHSGSCN
Protease-free N
Diervrij N
Vrij van nucleasen N
Dragervrij Y
Endotoxinevrij N
Endotoxinegehalte Endotoxin LAL (EU/µg) ≤0,1,Low
Endotoxinegehalte Endotoxin LAL (EU/µg) ≤0,1,Low
Biologische activiteiten Bioactivity Assay: Neutralization of Human Activin A induced cytotoxicity of MPC-11 cells, ED₅₀ ≤200 ng/ml, Bioactivity ≥5,0×10³ units/mg
Zuiverheid ≥95%
Nr RUO
Formulering 10 mM Sodium phosphate, 50 mM Sodium chloride, pH 7,5
Moleculair gewicht 31,7 kDa
Reconstitution instructions Sterile water at 0,1 mg/ml
Storage conditions –20 °C
Shipping temperature RT
Tested applications Bioassay

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