Human Recombinant IL-1RA (from E. coli)

Leverancier: Shenandoah Biotechnology
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100-195-20UG 100-195-100UG 100-195-250UG 100-195-500UG 100-195-1MG
SHBT100-195-20UGEA 72.4 EUR
SHBT100-195-20UG SHBT100-195-100UG SHBT100-195-250UG SHBT100-195-500UG SHBT100-195-1MG
Human Recombinant IL-1RA (from E. coli)
Eiwitten en peptiden

Interleukin-1 receptor antagonist (IL-1RA) binds the interleukin 1 receptor (IL-1R) to antagonize interleukin 1 alpha and beta signaling. IL-1RA is secreted by immune cells, epithelial cells, hepatocytes, and adipocytes to inhibit IL-1-induced inflammation. IL-1RA therapy is used to treat auto-inflammatory diseases such as diabetes and rheumatoid arthritis.


  • High quality
  • Low endotoxin
  • Affordable


IL-1RA is secreted by immune cells, epithelial cells, hepatocytes, and adipocytes to inhibit IL-1-induced inflammation. IL-1RA therapy is used to treat auto-inflammatory diseases such as diabetes and rheumatoid arthritis.


Leveringsinformatie: A COA is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.


Opgelet: For research use only.

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Specificaties

Protein/peptide name IL-1RA
Environmentally Preferable
Protein synonyms IL-1F3|IL1RN
Protein/peptide type Recombinant
Protein function Cytokine
Species Human
Bron E. coli
Conjugatie Onconjugeerd
Gen-ID P18510
Sequentie MRPSGRKSSK MQAFRIWDVN QKTFYLRNNQ LVAGYLQGPN VNLEEKIDVV PIEPHALFLG IHGGKMCLSC VKSGDETRLQ LEAVNITDLS ENRKQDKRFA FIRSDSGPTT SFESAACPGW FLCTAMEADQ PVSLTNMPDE GVMVTKFYFQ EDE
Protease-free N
Diervrij N
Vrij van nucleasen N
Dragervrij Y
Endotoxinevrij N
Endotoxinegehalte Endotoxin LAL (EU/µg) ≤1,Low
Endotoxinegehalte Endotoxin LAL (EU/µg) ≤1,Low
UniProtKB P18510
Biologische activiteiten Bioactivity assay: Inhibition of human IL-1 alpha induced proliferation of D10,G4,1 cells, ED50 ≤50 ng/ml, bioactivity ≥2,0×10⁴ units/mg
Zuiverheid ≥95%
Nr RUO
Formulering 10 mM sodium phosphate, pH 7,5
Moleculair gewicht 17,3 kDa
Reconstitution instructions Sterile water at 0,1 mg/ml
Storage conditions −20 °C
Shipping temperature RT
Tested applications Bioassay

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