SMER28 synthetic 98 TLC_ASSAY_METHOD
Leverancier: ENZO LIFE SCIENCESTotal Ratings: 0
Avg. Ratings: 0.0 out of 5
|
Gevaar
|
Synoniemen:
N-Allyl-6-bromoquinazolin-4-amine
Small molecule inducer of autophagy important for neurodegenerative disease research.
Chemical inducer of autophagy which acts via an mTOR-independent mechanism. It increased autophagosome synthesis and enhanced the clearance of model autophagy substrates such as A53T alpha-synuclein and mutant huntingtin fragments. It reduced Aβ peptide and AAP-CTF levels in an alzheimers model and attenuated mutant huntingtin-fragment toxicity in Huntington's disease models, suggesting therapeutic potential.
Soluble in DMSO (8 mg/ml) or 100% ethanol (2 mg/ml).
Formule:
C₁₁H₁₀BrN₃ MW: 264.126 g/mol Bewaar temperatuur: Vriezer |
MDL Nummer:
MFCD02166825 CAS nummer: 307538-42-7 |
|
Specification Test Results
Source | Synthetic |
Purity (TLC) | ≥98% |
Learn more

About VWR
Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...