Embelin ≥98%
Leverancier: ENZO LIFE SCIENCESTotal Ratings: 0
Avg. Ratings: 0.0 out of 5
Synoniemen:
2,5-Dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione
XIAP inhibitor
Embelin is a novel cell-permeable inhibitor of XIAP (X-linked inhibitor of apoptosis) which was discovered by screening a library of natural products derived from traditional Chinese medicine. It binds to the XIAP BIR3 domain preventing its binding to and inhibition of caspase-9 and effector caspases. Embelin selectively inhibits cell growth in cancer cells expressing high levels of XIAP (IC50 = 3-6 µM) versus normal cells with low levels of XIAP.
Formule:
C₁₇H₂₆O₄ MW: 294.40 g/mol |
MDL Nummer:
MFCD00016369 CAS nummer: 550-24-3 |
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