Embelin ≥98%

Leverancier: ENZO LIFE SCIENCES
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Total Ratings: 0
Avg. Ratings: 0.0 out of 5

Synoniemen: 2,5-Dihydroxy-3-undecylcyclohexa-2,5-diene-1,4-dione

BMLCM1250010 BMLCM1250050
ENZOBMLCM1250010EA 86.9 EUR
ENZOBMLCM1250010 ENZOBMLCM1250050
Embelin ≥98%
Embelin

XIAP inhibitor


Embelin is a novel cell-permeable inhibitor of XIAP (X-linked inhibitor of apoptosis) which was discovered by screening a library of natural products derived from traditional Chinese medicine. It binds to the XIAP BIR3 domain preventing its binding to and inhibition of caspase-9 and effector caspases. Embelin selectively inhibits cell growth in cancer cells expressing high levels of XIAP (IC50 = 3-6 µM) versus normal cells with low levels of XIAP.

Formule: C₁₇H₂₆O₄
MW: 294.40 g/mol
MDL Nummer: MFCD00016369
CAS nummer: 550-24-3
https://digitalassets.avantorsciences.com/adaptivemedia/rendition?id=23e842c3874128f7a4960387bba359a264d38ef6&vid=0e4a11c7f9101171427beb99759ad72712f95639&prid=web&clid=SAPDAM

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