Dynasore ≥98% (by NMR)

Leverancier: ENZO LIFE SCIENCES
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ALX270502M005 ALX270502M025
ENZOALX270502M005EA 73.7 EUR
ENZOALX270502M005 ENZOALX270502M025
Dynasore ≥98% (by NMR)
Dynasore

GTPase inhibitor


Small molecule GTPase inhibitor targeting Dynamin-1, Dynamin-2 and Drp1 (mitochondrial Dynamin). Noncompetitive inhibitor of Dynamin GTPase activity. Blocks Dynamin-dependent endocytosis in cells (including neurons). Fast acting (seconds). Strong, dose dependent block of the traffic and accumulation of transferrin with 80µM dynasore (IC50 = 15µM). Has also been shown to block human papillomavirus type 16 (HPV16) and bovine papillomavirus type 1 (BPV1) (pseudovirions) infections.

Formule: C₁₈H₁₄N₂O₄
MDL Nummer: MFCD00292551
CAS nummer: 304448-55-3

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