Amidepsine A 95 HPLC_ASSAY_METHOD
Leverancier: ENZO LIFE SCIENCES
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ALX380262M001
ALX380262MM25
ENZOALX380262M001EA
412
EUR
ENZOALX380262M001
ENZOALX380262MM25
Amidepsine A 95 HPLC_ASSAY_METHOD
Amidepsine A
DGAT inhibitor
Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC50=10.2µM) and Raji cells (IC50=15.5µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.
Isolated from fungal strain FO-2943.
Bestelinformatie: Fungal strain courtesy of the Kitasato Institute, Tokyo.
Formule:
C₂₉H₂₉NO₁₁ MW: 567.6 g/mol |
CAS nummer:
169181-28-6 |
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