Amidepsine A 95 HPLC_ASSAY_METHOD

Leverancier: ENZO LIFE SCIENCES
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ALX380262M001 ALX380262MM25
ENZOALX380262M001EA 412 EUR
ENZOALX380262M001 ENZOALX380262MM25
Amidepsine A 95 HPLC_ASSAY_METHOD
Amidepsine A

DGAT inhibitor


Inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC50=10.2µM) and Raji cells (IC50=15.5µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and hypertriglyceridemia, which may lead to atherosclerosis, diabetes and metabolic disorders.


Isolated from fungal strain FO-2943.


Bestelinformatie: Fungal strain courtesy of the Kitasato Institute, Tokyo.

Formule: C₂₉H₂₉NO₁₁
MW: 567.6 g/mol
CAS nummer: 169181-28-6

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