HA14-1 ≥95% (by 1H-NMR)
Leverancier: ENZO LIFE SCIENCES
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ALX430101M005
ALX430101M025
ENZOALX430101M005EA
84.7
EUR
ENZOALX430101M005
ENZOALX430101M025
HA14-1 ≥95% (by 1H-NMR)
HA14-1
Bcl-2 ligand
Antagonizes the function of Bcl-2 and induces apoptosis. In HL-60 cells, HA4-1 (50 µM and 4 h incubation) induced apoptosis of more than 90% of the cells. Apoptosis is blocked by ZVAD-FM. IC₅₀= ~9 µM for competition with Flu-BakBH3 binding to Bcl-2.
Soluble in DMSO (25 mg/ml), dimethyl formamide or halogenated solvents; also soluble in 100% ethanol (25 mg, 7 ml hot).
Formule:
C₁₇H₁₇BrN₂O₅ Bewaar temperatuur: Vriezer |
MDL Nummer:
MFCD00218213 CAS nummer: 65673-63-4 |
Specification Test Results
Purity (¹H-NMR) | ≥95% |
Identity | Identity determined by IR, ¹H-NMR |
Appearance | Off-white to light yellow powder |
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