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Catalogus nummer: (BOSSBS-0953R-CY5.5)

Leverancier: Bioss

Omschrijving: This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq].

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-13677R-CY5)

Leverancier: Bioss

Omschrijving: RUSC1 is a 902 amino acid protein that contains a RUN domain and a SH3 domain. RUSC1’s RUN domain is necessary for NGF induced nuclear redistribution. RUSC1 is a putative signaling adapter which may play a role in neuronal differentiation. RUSC1 seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. RUSC2 (RUN and SH3 domain containing 2), also known as Iporin, is a 1,516 amino acid cytoplasmic protein that is widely expressed, with highest levels in brain and testis. The RUN domain of RUSC2 is required for interaction with Rab 1A, Rab 1B and GM130. It is thought that RUSC2 may possibly function as a connector between endoplasmic reticulum (ER) derived vesicle targets triggered by the Rab 1 GTPases and a signaling pathway regulated by molecules containing SH3 and/or poly-proline regions. RUSC2 also consists of a SH3 domain, suggesting a role in protein-protein interactions.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-6088R-A350)

Leverancier: Bioss

Omschrijving: Probable inhibitory regulator of the Ras-cyclic AMP pathway.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-0948R-A488)

Leverancier: Bioss

Omschrijving: Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of GPR56 in the developing brain and binding to GPR56 inhibits neuronal migration and activates the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-13620R-HRP)

Leverancier: Bioss

Omschrijving: The C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily consists of a variety of proteins that share a common protein fold and have diverse functions, including cell-cell signaling, cell adhesion, glycoprotein turnover and immune responses. CLEC-9A (C-type lectin domain family 9 member A), also known as DNGR1 (dendritic cell natural killer lectin group receptor 1), is a 241 amino acid single-pass type II membrane protein that contains one C-type lectin domain and belongs to the CTL/CTLD superfamily. Expressed in myeloid lineage cells, brain, spleen and thymus, CLEC-9A is a group V C-type lectin-like receptor (CTLR) that acts as an activation receptor. The gene encoding CLEC-9A maps to human chromosome 12p13.2 and mouse chromosome 6 F3.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-2697R-A647)

Leverancier: Bioss

Omschrijving: The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and altered expression of this protein is associated with the disease cystic fibrosis. [provided by RefSeq, Jul 2008]

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-0953R-A350)

Leverancier: Bioss

Omschrijving: This gene is a member of the glycoprotein hormone beta chain family and encodes the beta 3 subunit of chorionic gonadotropin (CG). Glycoprotein hormones are heterodimers consisting of a common alpha subunit and an unique beta subunit which confers biological specificity. CG is produced by the trophoblastic cells of the placenta and stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. The beta subunit of CG is encoded by 6 genes which are arranged in tandem and inverted pairs on chromosome 19q13.3 and contiguous with the luteinizing hormone beta subunit gene. [provided by RefSeq].

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-0948R-CY5.5)

Leverancier: Bioss

Omschrijving: Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of GPR56 in the developing brain and binding to GPR56 inhibits neuronal migration and activates the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-2698R-CY5)

Leverancier: Bioss

Omschrijving: Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).

UOM: 1 * 100 µl

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Catalogus nummer: (ABCAAB77483-100)

Leverancier: Abcam

Omschrijving: Anti-UXT Goat Polyclonal Antibody

UOM: 1 * 1 EA

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Catalogus nummer: (BOSSBS-0112M-A680)

Leverancier: Bioss

Omschrijving: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-1761R-A750)

Leverancier: Bioss

Omschrijving: Chemotactic for activated T-lymphocytes. May play an important role in the collaboration of dendritic cells and B-lymphocytes with T-cells in immune responses.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-5706R-HRP)

Leverancier: Bioss

Omschrijving: The function of RASSF4 has not yet been determined but it may involve a role in tumor suppression. RASSF4 may act as a KRAS effector protein and may promote apoptosis and cell cycle arrest. Alternative splicing of this gene results in several transcript variants; however, most of the variants have not been fully described.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-5713R-A647)

Leverancier: Bioss

Omschrijving: HOXA5 upregulates both p53 promoter-reporter constructs and endogenous p53 synthesis, leading to apoptosis. HOXA5 is detectable in approximately one-third of primary tumors. Lack of HOXA5 expression strongly correlates with methylation of its promoter region, suggesting a causal role for methylation in the silencing of HOXA5 gene expression. HOXA5 expression is an important step in tumorigenesis and loss of expression of p53 in human breast cancer may be primarily due to lack of expression of HOXA5.

UOM: 1 * 100 µl

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Leverancier: US Biological

Omschrijving: Anti-Tumor Necrosis Factor Receptor 2, Soluble Rabbit Polyclonal Antibody (Biotin)

Catalogus nummer: (USBII8443-18K-25)

Leverancier: US Biological

Omschrijving: Anti-Interleukin 22 Rabbit Polyclonal Antibody (Biotin)

UOM: 1 * 1 EA

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