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Image Unavailable-BOSSBS-11822R-A488

Anti-CSAD Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Omschrijving: CSAD is a 493 amino acid protein that exists as a homodimer and belongs to the group II decarboxylase family. CSAD catalyzes the conversion of 3-sulfino-L-alanine to hypotaurine and carbon dioxide, binds pyridoxal phosphate as a cofactor and undergoes alternative splicing to produce three isoforms. The gene encoding CSAD maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Catalogus nummer: BOSSBS-11822R-A488
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-11822R-A750

Anti-CSAD Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Omschrijving: CSAD is a 493 amino acid protein that exists as a homodimer and belongs to the group II decarboxylase family. CSAD catalyses the conversion of 3-sulfino-L-alanine to hypotaurine and carbon dioxide, binds pyridoxal phosphate as a cofactor and undergoes alternative splicing to produce three isoforms. The gene encoding CSAD maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Catalogus nummer: BOSSBS-11822R-A750
UOM: 1 * 100 µl
Leverancier: Bioss
Product Image-AATB19007

Amplite® Fluorimetric Lead (II) Ion Quantitation Kit

Omschrijving: Lead is a highly poisonous metal to human beings, especially young children.
Catalogus nummer: AATB19007
UOM: 1 * 1 EA
Leverancier: AAT BIOQUEST
Image Unavailable-BOSSBS-11822R-A350

Anti-CSAD Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Omschrijving: CSAD is a 493 amino acid protein that exists as a homodimer and belongs to the group II decarboxylase family. CSAD catalyzes the conversion of 3-sulfino-L-alanine to hypotaurine and carbon dioxide, binds pyridoxal phosphate as a cofactor and undergoes alternative splicing to produce three isoforms. The gene encoding CSAD maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Catalogus nummer: BOSSBS-11822R-A350
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-15436R

Anti-HEAB Rabbit Polyclonal Antibody

Omschrijving: HEAB is a 425 amino acid nuclear protein that belongs to the Clp1 family. Utilizing magnesium, manganese or nickel as cofactors, HEAB participates in the phosphorylation of the 5'-hydroxyl groups of double- and single- stranded RNA and DNA. HEAB is a member of the tRNA splicing endonuclease complex, in conjunction with TSEN2, TSEN15, TSEN34 and TSEN54, and is also a member of the pre-mRNA cleavage complex II. The gene encoding HEAB maps to human chromosome 11q12.1 and mouse chromosome 2 D; mutations to this gene may lead to a reduced pre-mRNA cleavage activity. HEAB exists as two isoforms due to alternative splicing events.
Catalogus nummer: BOSSBS-15436R
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-15436R-A647

Anti-HEAB Rabbit Polyclonal Antibody (ALEXA FLUOR® 647)

Omschrijving: HEAB is a 425 amino acid nuclear protein that belongs to the Clp1 family. Utilising magnesium, manganese or nickel as cofactors, HEAB participates in the phosphorylation of the 5'-hydroxyl groups of double- and single- stranded RNA and DNA. HEAB is a member of the tRNA splicing endonuclease complex, in conjunction with TSEN2, TSEN15, TSEN34 and TSEN54, and is also a member of the pre-mRNA cleavage complex II. The gene encoding HEAB maps to human chromosome 11q12.1 and mouse chromosome 2 D; mutations to this gene may lead to a reduced pre-mRNA cleavage activity. HEAB exists as two isoforms due to alternative splicing events.
Catalogus nummer: BOSSBS-15436R-A647
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-15436R-A680

Anti-HEAB Rabbit Polyclonal Antibody (ALEXA FLUOR® 680)

Omschrijving: HEAB is a 425 amino acid nuclear protein that belongs to the Clp1 family. Utilising magnesium, manganese or nickel as cofactors, HEAB participates in the phosphorylation of the 5'-hydroxyl groups of double- and single- stranded RNA and DNA. HEAB is a member of the tRNA splicing endonuclease complex, in conjunction with TSEN2, TSEN15, TSEN34 and TSEN54, and is also a member of the pre-mRNA cleavage complex II. The gene encoding HEAB maps to human chromosome 11q12.1 and mouse chromosome 2 D; mutations to this gene may lead to a reduced pre-mRNA cleavage activity. HEAB exists as two isoforms due to alternative splicing events.
Catalogus nummer: BOSSBS-15436R-A680
UOM: 1 * 100 µl
Leverancier: Bioss
Product Image-80-6442-90

Toebehoren voor electroforese units, Multiphor™ II

Omschrijving: Anode and cathode electrode leads, Voor: Multiphor™ II electrophoresis unit
Catalogus nummer: 80-6442-90
UOM: 1 * 1 ST
Leverancier: Cytiva
Image Unavailable-BOSSBS-11822R-A680

Anti-CSAD Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Omschrijving: CSAD is a 493 amino acid protein that exists as a homodimer and belongs to the group II decarboxylase family. CSAD catalyses the conversion of 3-sulfino-L-alanine to hypotaurine and carbon dioxide, binds pyridoxal phosphate as a cofactor and undergoes alternative splicing to produce three isoforms. The gene encoding CSAD maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Catalogus nummer: BOSSBS-11822R-A680
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-11822R-HRP

Anti-CSAD Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Omschrijving: CSAD is a 493 amino acid protein that exists as a homodimer and belongs to the group II decarboxylase family. CSAD catalyzes the conversion of 3-sulfino-L-alanine to hypotaurine and carbon dioxide, binds pyridoxal phosphate as a cofactor and undergoes alternative splicing to produce three isoforms. The gene encoding CSAD maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Catalogus nummer: BOSSBS-11822R-HRP
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-11822R-FITC

Anti-CSAD Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Omschrijving: CSAD is a 493 amino acid protein that exists as a homodimer and belongs to the group II decarboxylase family. CSAD catalyzes the conversion of 3-sulfino-L-alanine to hypotaurine and carbon dioxide, binds pyridoxal phosphate as a cofactor and undergoes alternative splicing to produce three isoforms. The gene encoding CSAD maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Catalogus nummer: BOSSBS-11822R-FITC
UOM: 1 * 100 µl
Leverancier: Bioss
Product Image-PRSI27-199

Anti-FN3KRP Rabbit Polyclonal Antibody

Omschrijving: FN3KRP phosphorylates psicosamines and ribulosamines, but not fructosamines, on the third carbon of the sugar moiety. Protein-bound psicosamine 3-phosphates and ribulosamine 3-phosphates are unstable and decompose under physiological conditions. Thus phosphorylation leads to deglycation.FN3KRP and FN3K (MIM 608425) protect proteins from nonenzymatic glycation by phosphorylating the modified amino acid. This phosphorylation destabilizes the sugar-amine linkage and leads to spontaneous decomposition (Conner et al., 2004 [PubMed 15381090]).
Catalogus nummer: PRSI27-199
UOM: 1 * 1 EA
Leverancier: ProSci Inc.
Image Unavailable-BOSSBS-3216R-CY5

Anti-HDAC7 Rabbit Polyclonal Antibody (Cy5®)

Omschrijving: HDAC7 is a member of the class II mammalian histone deacetylases, which plays an important role in modulating the eukaryotic chromatin structure. Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. It is an active component of different transcriptional corepressor complexes that can be recruited to specific promoter regions via interactions with a growing number of sequence specific transcriptional factors. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription.
Catalogus nummer: BOSSBS-3216R-CY5
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-3216R-A350

Anti-HDAC7 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Omschrijving: HDAC7 is a member of the class II mammalian histone deacetylases, which plays an important role in modulating the eukaryotic chromatin structure. Human HDAC7 is composed of 912 amino acid residues. Although HDAC7 is localized mostly to the cell nucleus, it is also found in the cytoplasm, suggesting nucleo-cytoplasmic shuttling. The histone deacetylase activity of HDAC7 maps to a carboxy-terminal domain and is dependent on interaction with class I HDACs in the nucleus. It is an active component of different transcriptional corepressor complexes that can be recruited to specific promoter regions via interactions with a growing number of sequence specific transcriptional factors. HDAC7 catalyzes removal of acetyl-groups from acetyl-lysines of histones and promotes compaction of chromatin in these regions, leading to the inhibition of gene transcription.
Catalogus nummer: BOSSBS-3216R-A350
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-6252R-CY3

Anti-SIK1 Rabbit Polyclonal Antibody (Cy3®)

Omschrijving: Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, gluconeogenesis and lipogenesis regulation, muscle growth and differentiation and tumor suppression. Phosphorylates HDAC4, HDAC5, PPME1, SREBF1, CRTC1/TORC1 and CRTC2/TORC2. Acts as a tumor suppressor and plays a key role in p53/TP53-dependent anoikis, a type of apoptosis triggered by cell detachment: required for phosphorylation of p53/TP53 in response to loss of adhesion and is able to suppress metastasis. Part of a sodium-sensing signaling network, probably by mediating phosphorylation of PPME1: following increases in intracellular sodium, SIK1 is activated by CaMK1 and phosphorylates PPME1 subunit of protein phosphatase 2A (PP2A), leading to dephosphorylation of sodium/potassium-transporting ATPase ATP1A1 and subsequent increase activity of ATP1A1. Acts as a regulator of muscle cells by phosphorylating and inhibiting class II histone deacetylases HDAC4 and HDAC5, leading to promote expression of MEF2 target genes in myocytes. Also required during cardiomyogenesis by regulating the exit of cardiomyoblasts from the cell cycle via down-regulation of CDKN1C/p57Kip2. Acts as a regulator of hepatic gluconeogenesis by phosphorylating and repressing the CREB-specific coactivators CRTC1/TORC1 and CRTC2/TORC2, leading to inhibit CREB activity. Also regulates hepatic lipogenesis by phosphorylating and inhibiting SREBF1. In concert with CRTC1/TORC1, regulates the light-induced entrainment of the circadian clock by attenuating PER1 induction; represses CREB-mediated transcription of PER1 by phosphorylating and deactivating CRTC1/TORC1 (By similarity).
Catalogus nummer: BOSSBS-6252R-CY3
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-15436R-A555

Anti-HEAB Rabbit Polyclonal Antibody (ALEXA FLUOR® 555)

Omschrijving: HEAB is a 425 amino acid nuclear protein that belongs to the Clp1 family. Utilising magnesium, manganese or nickel as cofactors, HEAB participates in the phosphorylation of the 5'-hydroxyl groups of double- and single- stranded RNA and DNA. HEAB is a member of the tRNA splicing endonuclease complex, in conjunction with TSEN2, TSEN15, TSEN34 and TSEN54, and is also a member of the pre-mRNA cleavage complex II. The gene encoding HEAB maps to human chromosome 11q12.1 and mouse chromosome 2 D; mutations to this gene may lead to a reduced pre-mRNA cleavage activity. HEAB exists as two isoforms due to alternative splicing events.
Catalogus nummer: BOSSBS-15436R-A555
UOM: 1 * 100 µl
Leverancier: Bioss
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