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Image Unavailable-BOSSBS-9432R-A488

Anti-RNF27 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Omschrijving: The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM8 (tripartite motif containing 8), also known as GERP (glioblastoma-expressed RING finger protein) or RNF27 (RING finger protein 27), is a 551 amino acid protein that is thought to function as an E3 ubiquitin-protein ligase that promotes SOCS-1 proteasomal degradation. As a widely expressed homodimer, TRIM8 localizes to nuclear bodies and contains two B box-type zinc fingers and one RING-type zinc finger. TRIM8 is expressed in lung, heart, brain and skeletal muscle, with low levels detected in intestine, placenta, leukocytes and liver. The gene encoding TRIM8 maps to human chromosome 10q24.32.
Catalogus nummer: BOSSBS-9432R-A488
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-9432R-A350

Anti-RNF27 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Omschrijving: The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. TRIM8 (tripartite motif containing 8), also known as GERP (glioblastoma-expressed RING finger protein) or RNF27 (RING finger protein 27), is a 551 amino acid protein that is thought to function as an E3 ubiquitin-protein ligase that promotes SOCS-1 proteasomal degradation. As a widely expressed homodimer, TRIM8 localizes to nuclear bodies and contains two B box-type zinc fingers and one RING-type zinc finger. TRIM8 is expressed in lung, heart, brain and skeletal muscle, with low levels detected in intestine, placenta, leukocytes and liver. The gene encoding TRIM8 maps to human chromosome 10q24.32.
Catalogus nummer: BOSSBS-9432R-A350
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-9230R-CY5.5

Anti-RNF158 Rabbit Polyclonal Antibody (Cy5.5®)

Omschrijving: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. SH3RF2 (SH3 domain containing ring finger 2), also known as RNF158, is a 729 amino acid protein with one RING-type zinc finger domain and three SH3 domains. Via its RING-type zinc finger domain, SH3RF2 binds an E2 ubiquitin-conjugating enzyme. This suggests that SH3RF2 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation. Due to alternative splicing events, SH3RF2 is expressed as two different isoforms.
Catalogus nummer: BOSSBS-9230R-CY5.5
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-9230R-A488

Anti-RNF158 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Omschrijving: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. SH3RF2 (SH3 domain containing ring finger 2), also known as RNF158, is a 729 amino acid protein with one RING-type zinc finger domain and three SH3 domains. Via its RING-type zinc finger domain, SH3RF2 binds an E2 ubiquitin-conjugating enzyme. This suggests that SH3RF2 functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and immediately transfers that residue to a protein that is targeted for degradation. Due to alternative splicing events, SH3RF2 is expressed as two different isoforms.
Catalogus nummer: BOSSBS-9230R-A488
UOM: 1 * 100 µl
Leverancier: Bioss
Product Image-PRSI25-813

Anti-RFPL4B Rabbit Polyclonal Antibody

Omschrijving: RFPL4B contains 1 B30.2/SPRY domain and 1 RING-type zinc finger. The function of RFPL4B remains unknown.
Catalogus nummer: PRSI25-813
UOM: 1 * 1 EA
Leverancier: ProSci Inc.
Product Image-PRSI27-483

Anti-NAB1 Rabbit Polyclonal Antibody

Omschrijving: NAB1 belongs to the NAB family and acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2.
Catalogus nummer: PRSI27-483
UOM: 1 * 1 EA
Leverancier: ProSci Inc.
Image Unavailable-BOSSBS-11753R

Anti-RNF135 Rabbit Polyclonal Antibody

Omschrijving: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF135 (RING finger protein 135), also known as L13, is a 432 amino acid protein that contains one RING-type zinc finger and one SPRY domain. Via its RING-type zinc finger, RNF135 may play a role in transcriptional regulation and protein degradation events. Defects in the gene encoding RNF135 are the cause of RNF135-related overgrowth syndrome which is characterized by learning disabilities, facial dysmorphism and increased weight and height. Multiple isoforms of RNF135 exist due to alternative splicing events.
Catalogus nummer: BOSSBS-11753R
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-13569R

Anti-ZBTB26 Rabbit Polyclonal Antibody

Omschrijving: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. Zinc finger and BTB domain-containing protein 26 (ZBTB26), also known as ZNF481, is a 441 amino acid member of the Krüppel C2H2-type zinc-finger protein family. Localized to the nucleus, ZBTB26 contains a BTB domain, also known as a POZ domain, which inhibits DNA binding and mediates homotypic and heterotypic dimerization. Characteristics of the BTB domain suggest that ZBTB26 functions as a transcription regulator.
Catalogus nummer: BOSSBS-13569R
UOM: 1 * 100 µl
Leverancier: Bioss
Product Image-PRSI30-746

Anti-MICALL1 Rabbit Polyclonal Antibody

Omschrijving: MICALL1 contains 1 CH (calponin-homology) domain and 1 LIM zinc-binding domain. It may be a cytoskeletal regulator.
Catalogus nummer: PRSI30-746
UOM: 1 * 1 EA
Leverancier: ProSci Inc.
Image Unavailable-BOSSBS-11753R-CY3

Anti-RNF135 Rabbit Polyclonal Antibody (Cy3®)

Omschrijving: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF135 (RING finger protein 135), also known as L13, is a 432 amino acid protein that contains one RING-type zinc finger and one SPRY domain. Via its RING-type zinc finger, RNF135 may play a role in transcriptional regulation and protein degradation events. Defects in the gene encoding RNF135 are the cause of RNF135-related overgrowth syndrome which is characterized by learning disabilities, facial dysmorphism and increased weight and height. Multiple isoforms of RNF135 exist due to alternative splicing events.
Catalogus nummer: BOSSBS-11753R-CY3
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-12219R-CY7

Anti-ZNF426 Rabbit Polyclonal Antibody (Cy7®)

Omschrijving: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF426 (Zinc finger protein 426), also known as MGC2663, is a 554 amino acid protein that is thought to be involved in transcriptional regulation. Localized to the nucleus, ZNF426 contains one KRAB domain and 12 C2H2-type zinc fingers through which it may convey DNA, RNA and protein binding capabilities. Specifically, ZNF426 may interact with the viral protein KSHV ORF 50 and, through this interaction, may activate viral gene transcription.
Catalogus nummer: BOSSBS-12219R-CY7
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-12219R-A680

Anti-ZNF426 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Omschrijving: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF426 (Zinc finger protein 426), also known as MGC2663, is a 554 amino acid protein that is thought to be involved in transcriptional regulation. localised to the nucleus, ZNF426 contains one KRAB domain and 12 C2H2-type zinc fingers through which it may convey DNA, RNA and protein binding capabilities. Specifically, ZNF426 may interact with the viral protein KSHV ORF 50 and, through this interaction, may activate viral gene transcription.
Catalogus nummer: BOSSBS-12219R-A680
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-9379R-HRP

Anti-MKRN2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Omschrijving: The Makorins are a family of putative ribonucleoproteins containing two to four C3H zinc fingers that may confer RNA-binding. In addition, they contain a C3HC4 RING zinc finger that allows them to function as E3 ubiquitin ligases. Makorin-2, also known as RNF62, HSPC070 or MKRN2, is a widely expressed, evolutionarily conserved protein with four C3H-type zinc fingers (three at the N-terminus and one at the C-terminus), one RING-type zinc finger and a cysteine and histidine motif similar to that found in Makorin-1. In Xenopus, Makorin-2 functions, via PI 3-kinase/Akt signaling, as a negative regulator of neurogenesis. In humans, Makorin-2 is overexpressed in various cancer cell lines, suggesting a possible role of Makorin-2 in tumor progression. In addition, Makorin-2 is co-expressed with Raf-1 in the same tissues and cell lines.
Catalogus nummer: BOSSBS-9379R-HRP
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-12219R

Anti-ZNF426 Rabbit Polyclonal Antibody

Omschrijving: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF426 (Zinc finger protein 426), also known as MGC2663, is a 554 amino acid protein that is thought to be involved in transcriptional regulation. Localized to the nucleus, ZNF426 contains one KRAB domain and 12 C2H2-type zinc fingers through which it may convey DNA, RNA and protein binding capabilities. Specifically, ZNF426 may interact with the viral protein KSHV ORF 50 and, through this interaction, may activate viral gene transcription.
Catalogus nummer: BOSSBS-12219R
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-11669R-FITC

Anti-RNF146 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Omschrijving: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF146 (RING finger protein 146), also known as Dactylidin, is a 359 amino acid protein that contains one RING-type zinc finger and one WWE domain. Via its RING-type zinc finger, RNF146 may play a role in transcriptional regulation and protein degradation events. Defects in the gene encoding RNF146 are associated with Alzheimer's disease (AD) and may lead to a higher risk of breast cancer. Two isoforms of RNF146 exist due to alternative splicing events.
Catalogus nummer: BOSSBS-11669R-FITC
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-11753R-FITC

Anti-RNF135 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Omschrijving: The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF135 (RING finger protein 135), also known as L13, is a 432 amino acid protein that contains one RING-type zinc finger and one SPRY domain. Via its RING-type zinc finger, RNF135 may play a role in transcriptional regulation and protein degradation events. Defects in the gene encoding RNF135 are the cause of RNF135-related overgrowth syndrome which is characterized by learning disabilities, facial dysmorphism and increased weight and height. Multiple isoforms of RNF135 exist due to alternative splicing events.
Catalogus nummer: BOSSBS-11753R-FITC
UOM: 1 * 100 µl
Leverancier: Bioss
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