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Leverancier: STEMCELL Technologies

Omschrijving: Rat monoclonal IgG2a antibody against mouse CD19, FITC-conjugated.

Leverancier: STEMCELL Technologies

Omschrijving: Mouse monoclonal IgG2b, kappa isotype control antibody, unconjugated.

Leverancier: STEMCELL Technologies

Omschrijving: Mouse monoclonal IgG2b antibody against human CD68, FITC-conjugated.

Leverancier: STEMCELL Technologies

Omschrijving: Mouse monoclonal IgG1 antibody against human, rhesus, cynomolgus CD11b, Alexa Fluor® 488-conjugated.

Leverancier: STEMCELL Technologies

Omschrijving: Rat monoclonal IgG2a antibody against human, mouse, rhesus CD49f, FITC-conjugated.

Leverancier: STEMCELL Technologies

Omschrijving: Mouse monoclonal IgG1 antibody against human, chimpanzee CD19, PE­conjugated.

Leverancier: STEMCELL Technologies

Omschrijving: Mouse monoclonal IgG1 antibody against human, chimpanzee CD33, FITC-conjugated.

Catalogus nummer: (STMC03950)

Leverancier: STEMCELL Technologies

Omschrijving: Serum-free media for suspension culture of human ES and iPS cells.

UOM: 1 * 1 Kit

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Leverancier: STEMCELL Technologies

Omschrijving: Fibroblast growth factor 4 (FGF-4) is a member of the FGF superfamily (Beenken and Mohammadi). FGF-4 is expressed in pluripotent stem cells and is implicated in various stages of development and morphogenesis in a variety of organisms (Kosaka <i>et al.</i> 2009). FGF-4 has been shown to have an ability to promote neural stem cell proliferation and neuronal differentiation in the postnatal brain (Kosaka <i>et al.</i> 2006). FGF-4 has also been shown to increase the proliferation rate of mesenchymal stem cells (Farré <i>et al.</i>). FGF-4 supports the maintenance and self-renewal properties of human embryonic stem cells and also promotes the proliferation of these cells (Mayshar <i>et al.</i>). In the mouse, the Fgf4 gene also supports proliferation of the inner cell mass (ICM) and postimplantation embryos (Feldman <i>et al.</i>).

Leverancier: STEMCELL Technologies

Omschrijving: Rat monoclonal IgM antibody against mouse CD43, biotin-conjugated.

Leverancier: STEMCELL Technologies

Omschrijving: Vascular endothelial growth factor (VEGF-165) is a heparin-binding homodimeric glycoprotein involved in embryonic vasculogenesis and angiogenesis. VEGF binds to VEGFR-1 (R1) and VEGFR-2 (R2), and activates Raf/MEK/ERK and PI3K/AKT pathways (Ferrara <i>et al.</i>). It plays an important role in neurogenesis both in vitro and in vivo (Storkebaum <i>et al.</i>). It has neurotrophic effects on neurons of the central nervous system and promotes growth and survival of dopaminergic neurons and astrocytes. VEGF also promotes growth and survival of vascular endothelial cells, monocyte chemotaxis, and colony formation by granulocyte-macrophage progenitor cells (Ferrara <i>et al.</i>).

Leverancier: STEMCELL Technologies

Omschrijving: Mouse monoclonal IgM, kappa isotype control antibody, PE-conjugated.

Leverancier: STEMCELL Technologies

Omschrijving: Rat monoclonal IgG1 antibody against mouse CD25, APC-conjugated.

Leverancier: STEMCELL Technologies

Omschrijving: Sonic hedgehog (Shh) is a member of the Hedgehog family of secreted signaling proteins that has a prominent role in patterning during early mammalian development (Ho and Scott). It is expressed during early embryogenesis in a variety of tissues (Finco <i>et al.</i>). During patterning of the central nervous system, Shh directly acts on cells to specify neural cell fates, regulates proliferation and survival of oligodendrocyte precursors and neural crest cells and stimulates proliferation, differentiation, and axon growth (Ho and Scott; Martí). Shh also regulates T cell differentiation and activation (Crompton <i>et al.</i>). Recombinant Mouse Shh is a fully biologically active molecule.

Leverancier: STEMCELL Technologies

Omschrijving: Monocyte chemotactic protein-1 (MCP-1), also known as CCL2, is a member of the CC family of chemokines. The protein is primarily induced by platelet-derived growth factor (PDGF) gene (Cochran <i>et al.</i>). The biological effects of MCP-1 are mediated via the specific G-protein-coupled receptor CCR2 which in turn activates signal transduction pathways leading to monocyte transmigration (Sozzani <i>et al.</i>). Migration of monocytes from the bloodstream across the vascular endothelium is required for routine immunological surveillance of tissues, as well as other immunomodulatory effects. MCP-1 is produced by a variety of cell types, including fibroblasts and endothelial, epithelial, smooth muscle, mesangial, astrocytic, monocytic, and microglial cells, which are important for antiviral responses in the peripheral circulations and in tissues (Cushing <i>et al.</i>; Deshmane <i>et al.</i>). MCP-1 plays a role in physiological processes such as neurogenesis, neuroprotection, and neurotransmission and has important implications in neurological disorders such as multiple sclerosis and Alzheimer’s disease, in which it is produced during neuroinflammation at the sites of lesions (Conductier <i>et al.</i>).

Leverancier: STEMCELL Technologies

Omschrijving: Rat monoclonal IgM antibody against mouse CD49b (integrin α2), APC-conjugated.