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Omschrijving: Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).
Catalogus nummer: BOSSBS-6139R-CY5
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Histone demethylase that demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9' or H3 'Lys-27'. Demethylates trimethylated, dimethylated and monomethylated H3 'Lys-4'. Acts as a transcriptional corepressor for FOXG1B and PAX9. Favors the proliferation of breast cancer cells by repressing tumor suppressor genes such as BRCA1 and HOXA5. In contrast, may act as a tumor suppressor for melanoma. Represses the CLOCK-ARNTL/BMAL1 heterodimer-mediated transcriptional activation of the core clock component PER2 (By similarity).
Catalogus nummer: BOSSBS-6139R-A488
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.
Catalogus nummer: BOSSBS-8352R-CY5
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. <i>in vitro</i> catalyzes 'Lys-11'- and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. Participates in the regulation of transepithelial sodium transport in renal cells. May be involved in cell growth arrest.
Catalogus nummer: BOSSBS-8352R-A750
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Anti-Ly-6K Rabbit Polyclonal Antibody
Catalogus nummer: ABCAAB224402-100
UOM: 1 * 100 µl
Leverancier: Abcam


Omschrijving: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognising and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilising p53/TP53 and increasing p53/TP53-mediated transcriptional activation. Also able to demethylated 'Lys-372' of p53/TP53 <i>in vitro</i>.
Catalogus nummer: BOSSBS-6191R-A680
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Deubiquitinating enzyme that functions as negative regulator of the innate immune system. Acts via TRAF3 deubiquitination and subsequent suppression of type I interferon (IFN) production. Has peptidase activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Can also cleave 'Lys-11'-linked ubiquitin chains (in vitro).
Catalogus nummer: BOSSBS-17566R-A750
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: L(+)-Lysine monohydrate ≥97%
Catalogus nummer: A13040.22
UOM: 1 * 100 g
Leverancier: Thermo Fisher Scientific

Omschrijving: (S)-Methyl-2-amino-6-(((benzyloxy)carbonyl)amino)hexanoate hydrochloride 95%
Catalogus nummer: L09744.03
UOM: 1 * 1 g
Leverancier: Thermo Fisher Scientific

Omschrijving: Anti-Ly-6A/E (Sca-1) Rat Monoclonal Antibody [clone: D7] (FITC)
Catalogus nummer: ABCAAB268016-50
UOM: 1 * 1 EA
Leverancier: Abcam


Omschrijving: Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor and is involved in regulating growth hormone release. Ghrelin is derived from a preprohormone called preproghrelin, which also generates a second peptide called obestatin. Obestatin is an endogenous ligand for the orphan G protein-coupled receptor GPR39 and is involved in satiety and decreased food intake. Also known as Appetite regulating hormone; GHRL; Growth hormone releasing peptide; Growth hormone secretagogue; M46 protein; Motilin related peptide; MTLRP; Obestatin; Obestatin preprohormone; PRO1066; UNQ524. Sequence notes: Gly-Ser-Ser-Phe-Leu-Ser-Pro- Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu- Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro- Arg (mo, rat).
Catalogus nummer: BOSSBS-1375R-A555
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Lucifer Yellow CH potassium salt (LY CH potassium salt) is a widely used polar molecular tracer for studying neuronal morphology. The fluorescent molecule contains a carbohydrazide that allow the molecule to be aldehyde-fixable.
Catalogus nummer: 80016.
UOM: 1 * 25 mg
Leverancier: Biotium


Omschrijving: Glandular kallikreins cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin.
Catalogus nummer: BOSSBS-1963R-A680
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Catalogus nummer: BOSSBS-7778R-CY3
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
Catalogus nummer: BOSSBS-7832R-CY5.5
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA.
Catalogus nummer: BOSSBS-2578R-CY3
UOM: 1 * 100 µl
Leverancier: Bioss