U heeft gezocht op: 8-Bromoadenosine+3\',5\'-cyclic+Monophosphothioate,+Rp-Isomer+sod

Leverancier: ENZO LIFE SCIENCES

Omschrijving: Inhibitor of cAMP-dependent protein kinase (PKA), preferentially binding to type I PKA. Lipophilic analog of Rp-cAMPS. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases. Significantly more lipophilic and membrane permeant as compared to Rp-cAMPS or 8-Br-cAMP.

Catalogus nummer: (ENZOALX480025M001)

Leverancier: ENZO LIFE SCIENCES

Omschrijving: PKA activator.

UOM: 1 * 1 mg

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Catalogus nummer: (ENZOALX480072M001)

Leverancier: ENZO LIFE SCIENCES

Omschrijving: Inhibitor of cGMP-dependent protein kinase (PKG) 1α (cGMP antagonist). Resistant against mammalian cyclic nucleotid-dependent phosphodiesterases. No metabolic side effects. Low membrane permeability.

UOM: 1 * 1 mg

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Catalogus nummer: (ENZOBMLCN2060001)

Leverancier: ENZO LIFE SCIENCES

Omschrijving: A cell-permeable cGMP antagonist which is resistant to hydrolysis by cyclic nucleotide phosphodiesterases (Ki=0.5 µM). No metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS

UOM: 1 * 1 mg

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Leverancier: ENZO LIFE SCIENCES

Omschrijving: Potent selective inhibitor of cGMP-dependent protein kinase 1α, 1β and type II. Resistant to mammalian cyclic nucleotide-dependent phosphodiesterases, no metabolic side effects. Significantly more lipophilic and membrane permeant as compared to Rp-cGMPS or Rp-8-Br-cGMPS.

Catalogus nummer: (ENZOALX480085M001)

Leverancier: ENZO LIFE SCIENCES

Omschrijving: Competitive inhibitor of cyclic AMP-dependent protein kinase I and II.Metabolic stability towards mammalian cyclic nucleotide- responsive phosphodiesterases.
Discriminates between protein kinase A (antagonist) and some other cyclic AMP receptors, e.g. channels or CAP 3 (agonist).Membrane-permeant for several systems (for improved permeability more lipophilic analogues e.g. Rp-8-Br-cAMPS are recommended).

UOM: 1 * 1 mg

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Leverancier: ENZO LIFE SCIENCES

Omschrijving: PKA activator.

Leverancier: TCI

Omschrijving: Tetraethylenepentamine (mixture of branched chain isomers and cyclic compounds)

Leverancier: TCI

Omschrijving: 4-Methyl-1,3,2-dioxathiolane-2-oxide (mixture of isomers) ≥98.0% (by GC)

Leverancier: Apollo Scientific

Omschrijving: 4-Methyl-1,3,2-dioxathiolane-2-oxide (mixture of isomers) 98%

Catalogus nummer: (ENZOBMLCN1350001)

Leverancier: ENZO LIFE SCIENCES

Omschrijving: Rp-cAMPS is a potent and specific competitive inhibitor of the activation of cAMP-dependent protein kinases by cAMP (IC50=4.9 µM) . Its cell permeability and complete resistance to cyclic nucleotide phosphodiesterases make it a unique tool for studying cAMP-dependent signaling. Significantly more lipophilc as compared to cAMP and thus membrane permeable in many biological systems. This product is not sterile.

UOM: 1 * 1 mg

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Catalogus nummer: (ENZOBMLCN2160500)

Leverancier: ENZO LIFE SCIENCES

Omschrijving: Cell-permeable, phosphodiesterase-resistant cGMP antagonist. Reversed NO stimulation of random migration in rabbit neutrophils. Used at 30µM to cometively inhibit 8-Br-cGMP relaxation of rabbit aortas. The product is not sterile. Resistant to nucleotide-dependent phosphodiesterases; no metabolic side effects. Significantly more lipophilic and membrane permeant as compared to cyclic GMP or Rp-cGMPS.

UOM: 1 * 1 EA

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Leverancier: Merck

Omschrijving: Purospher® STAR RP-8 endcapped is net als Purospher® STAR RP-18 endcapped gebaseerd op zeer zuivere silica en een bijna volledige dekking van het oppervlak. Purospher® STAR RP-8 biedt een uitstekende pieksymmetrie voor zure, basische en zelfs chelaterende verbindingen, de hoogste kolomefficiëntie wat betreft het aantal theoretische platen, en uitzonderlijke stabiliteit van pH 1,5 tot 10,5. Bovendien bieden Purospher® STAR RP-8 endcapped-kolommen een brede toepasbaarheid. Aangezien de sorbent minder hydrofoob is dan Purospher® STAR RP-18 endcapped, zullen analyten normaal gesproken sneller elueren op de C8-fase. Purospher® STAR RP-8 endcapped biedt een verbeterde selectiviteit voor positionele isomeren en symmetrische piekvormen voor sterk basische en minder hydrofobe verbindingen.

MSDS

Leverancier: Thermo Fisher Scientific

Omschrijving: 8-Bromoadenosine 98%

MSDS

Catalogus nummer: (BOSSBS-11332R-A350)

Leverancier: Bioss

Omschrijving: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-11332R-CY7)

Leverancier: Bioss

Omschrijving: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.

UOM: 1 * 100 µl

Sale