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Catalogus nummer: (BOSSBS-2390R)
Leverancier: Bioss
Omschrijving: ACO2, also referred to as aconitate hydratase, citrate hydrolyase or aconitase, is an iron-sulfur hydrolyase that catalyzes the non-limiting interconversion of citrate and isocitrate in the tricarboxylic acid cycle. It is expressed in the mitochondria and maintains a citrate:isocitrate ratio of approximately 10:1. ACO2 contains a redox-sensitive iron-sulfur cluster that exists in two states: active (Fe4S4) and inactive (Fe3S4). ACO2 activity is dependent on the state of this cluster as well as the presence of two conserved cysteine residues. In normal prostate epithelial cells ACO2 activity is prevented due to the high levels of zinc inhibiting the enzyme. In these citrate-producing epithelial cells citrate oxidation is impaired allowing citrate to accumulate and exhibit a citrate:isocitrate ratio of approximately 30:1. In malignant prostate cells zinc is unable to accumulate, therefore ACO2 activity resumes and citrate is oxidized.
UOM: 1 * 100 µl


Catalogus nummer: (AVIVARP36712_P050)
Leverancier: Aviva Systems Biology
Omschrijving: Anti-ADAR Rabbit Polyclonal Antibody
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-12957R)
Leverancier: Bioss
Omschrijving: Iron metabolism is essential for sustaining mammalian homeostasis. Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins; iron regulatory protein-1 and -2 (IRP-1 and -2), also known as iron responsive element-binding protein-1 and -2 (IRE–BP-1 and -2) or aconitase 1 and 2. IRP-1 and IRP-2 are important soluble regulatory factors that mediate iron uptake and storage in mammalian cells. They are capable of either repressing translation or enhancing mRNA stability by associating with stem-loop motifs known as iron-responsive elements (IREs). IRPs respond to stress mediators, iron concentration and signaling factors, including nitrogen monoxide, cytokines and hydrogen peroxide.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-12958R)
Leverancier: Bioss
Omschrijving: Iron metabolism is essential for sustaining mammalian homeostasis. Iron uptake and distribution is a highly regulated process in mammalian cells that is monitored by two iron sensing proteins; iron regulatory protein-1 and -2 (IRP-1 and -2), also known as iron responsive element-binding protein-1 and -2 (IRE–BP-1 and -2) or aconitase 1 and 2. IRP-1 and IRP-2 are important soluble regulatory factors that mediate iron uptake and storage in mammalian cells. They are capable of either repressing translation or enhancing mRNA stability by associating with stem-loop motifs known as iron-responsive elements (IREs). IRPs respond to stress mediators, iron concentration and signaling factors, including nitrogen monoxide, cytokines and hydrogen peroxide.
UOM: 1 * 100 µl


Catalogus nummer: (USBI122989)
Leverancier: US Biological
Omschrijving: Anti-ADAR Rabbit Polyclonal Antibody
UOM: 1 * 1 EA


Catalogus nummer: (HONCR1652-10MG)
Leverancier: Honeywell Chemicals
Omschrijving: High quality organic reference materials produced according to ISO 9001.
UOM: 1 * 10 mg


Catalogus nummer: (ANTIA324183-100)
Leverancier: ANTIBODIES.COM
Omschrijving: Anti-PDGF B Human Recombinant Monoclonal Antibody [clone: MOR-8457]
UOM: 1 * 1 EA

New Product


Catalogus nummer: (AVIVARP56301_P050)
Leverancier: Aviva Systems Biology
Omschrijving: Anti-ACO2 Rabbit Polyclonal Antibody
UOM: 1 * 100 µl


Catalogus nummer: (USBIA0660-02E)
Leverancier: US Biological
Omschrijving: Anti-ACO2 Rabbit Polyclonal Antibody
UOM: 1 * 1 EA


Catalogus nummer: (USBIA0660-02C)
Leverancier: US Biological
Omschrijving: Anti-ACO2 Rabbit Polyclonal Antibody
UOM: 1 * 200 µl


Leverancier: TriLink BioTechnologies
Omschrijving: Renilla luciferase (Renilla Luc) is a bioluminescent reporter protein derived from Renilla reniformis (sea pansy). In the presence of the cofactor, coelenterazine, Renilla luciferase produces light. Renilla Luc mRNA can be used as an internal control in combination with FLuc mRNA to test different conditions, such as dosage or chemical modifications, and their effect on translation.

New Product

Catalogus nummer: (ORIGCF507142)
Leverancier: OriGene
Omschrijving: Anti-AMOT Mouse Monoclonal Antibody [clone: 3F9]
UOM: 1 * 1 EA


Catalogus nummer: (USBI123283)
Leverancier: US Biological
Omschrijving: Anti-AMFR Mouse Monoclonal Antibody [clone: 3D9]
UOM: 1 * 1 EA


Catalogus nummer: (USBI031849-APC)
Leverancier: US Biological
Omschrijving: Anti-AMOT Rabbit Polyclonal Antibody (APC (Allophycocyanin))
UOM: 1 * 200 µl


Catalogus nummer: (AVIVARP40390_P050)
Leverancier: Aviva Systems Biology
Omschrijving: Anti-ACO1 Rabbit Polyclonal Antibody
UOM: 1 * 100 µl


Catalogus nummer: (USBIA0660-01E)
Leverancier: US Biological
Omschrijving: Anti-ACO1 Rabbit Polyclonal Antibody
UOM: 1 * 1 EA


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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