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Image Unavailable-BOSSBS-13048R-A750

Anti-ECH1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Omschrijving: ECH1 is a 328 amino acid protein that localizes to both the mitochondrion and the peroxisome and belongs to the hydratase/isomerase superfamily. Existing as a homohexamer, ECH1 is involved in the fatty acid-beta oxidation pathway, specifically functioning to catalyze the isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA. The gene encoding ECH1 maps to human chromosome 19, which is the genetic home for a number of immunoglobulin superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs).
Catalogus nummer: BOSSBS-13048R-A750
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-3737R-HRP

Anti-PPARG Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Omschrijving: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses.
Catalogus nummer: BOSSBS-3737R-HRP
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-4888R-CY5.5

Anti-PPARG Rabbit Polyclonal Antibody (Cy5.5®)

Omschrijving: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated proinflammatory responses.
Catalogus nummer: BOSSBS-4888R-CY5.5
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-0494R-FITC

Anti-ETFA Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Omschrijving: ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electrons between primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinone oxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in which multiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Catalogus nummer: BOSSBS-0494R-FITC
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-3936R-A680

Anti-SLC27A2/ACSVL1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Omschrijving: Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).
Catalogus nummer: BOSSBS-3936R-A680
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-3936R-A488

Anti-SLC27A2 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Omschrijving: Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).
Catalogus nummer: BOSSBS-3936R-A488
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-3936R-A350

Anti-SLC27A2 Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Omschrijving: Acyl-CoA synthetase probably involved in bile acid metabolism. Proposed to activate C27 precurors of bile acids to their CoA thioesters derivatives before side chain cleavage via peroxisomal beta-oxidation occurs. In vitro, activates 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate (THCA), the C27 precursor of cholic acid deriving from the de novo synthesis from cholesterol. Does not utilize C24 bile acids as substrates. In vitro, also activates long- and branched-chain fatty acids and may have additional roles in fatty acid metabolism. May be involved in translocation of long-chain fatty acids (LFCA) across membranes (By similarity).
Catalogus nummer: BOSSBS-3936R-A350
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-11987R-A488

Anti-CAPON Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Omschrijving: CAPON (carboxy-terminal PDZ ligand of nNOS) selectively binds within the 100 amino acid PDZ domain of the neuronal nitric oxide synthase (nNOS), but not to endothelial NOS or inducible NOS, and sequesters nNOS in the cytosol. Biosynthesis of the neurotransmitter nitric oxide (NO) requires the association of nNOS with various synaptic proteins, including syntrophin, postsynaptic density (PSD)95 and PSD93 through a scaffolding PDZ domain. These proteins facilitate the transport of nNOS to the plasma membrane, where it is catalytically activated by NMDA-receptor mediated calcium channels. The association of nNOS with PSD95 or PSD93 is regulated by CAPON. The carboxy terminus of CAPON binds to the PDZ domain, competes with PSD95 and PSD93 for binding to nNOS and in turn prevents the translocation and catalytic activation of nNOS.
Catalogus nummer: BOSSBS-11987R-A488
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-12448R-CY7

Anti-ADH5 Rabbit Polyclonal Antibody (Cy7®)

Omschrijving: The alcohol dehydrogenase family of proteins metabolize a wide variety of substrates, including retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. ADH5 (alcohol dehydrogenase 5 (class III)), also known as FDH (formaldehyde dehydrogenase), ADHX, ADH-3 or GSNOR, is a 374 amino acid cytoplasmic protein that belongs to the class III subfamily of alcohol dehydrogenases. Expressed ubiquitously, ADH5 uses iron as a cofactor to catalytically oxidize both long-chain primary alcohols and S-hydroxymethyl-glutathione, a product formed spontaneously between formaldehyde and glutathione. ADH5 exists as a homodimer and, via its ability to oxidize S-hydroxymethyl-glutathione and, thus, eliminate formaldehyde, functions as an important component of cellular metabolism. Genetic variations in the gene encoding ADH5 may affect drug and alcohol dependence in humans.
Catalogus nummer: BOSSBS-12448R-CY7
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-2589R-CY5.5

Anti-CYP1A2 Rabbit Polyclonal Antibody (Cy5.5®)

Omschrijving: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.
Catalogus nummer: BOSSBS-2589R-CY5.5
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-5045R-CY7

Anti-CPT1B Rabbit Polyclonal Antibody (Cy7®)

Omschrijving: The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene. [provided by RefSeq, Jun 2009].
Catalogus nummer: BOSSBS-5045R-CY7
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-8.20054.1000

Aluminium tri-sec-butanolate for synthesis, Sigma-Aldrich®

Omschrijving: Aluminium tri-sec-butanolate for synthesis, Sigma-Aldrich®
Catalogus nummer: 8.20054.1000
UOM: 1 * 1 L
Leverancier: Merck

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Image Unavailable-BOSSBS-3614R-CY7

Anti-PPARA Rabbit Polyclonal Antibody (Cy7®)

Omschrijving: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
Catalogus nummer: BOSSBS-3614R-CY7
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-3614R-HRP

Anti-PPARA Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Omschrijving: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
Catalogus nummer: BOSSBS-3614R-HRP
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-4055R-CY7

Anti-PPARA Rabbit Polyclonal Antibody (Cy7®)

Omschrijving: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
Catalogus nummer: BOSSBS-4055R-CY7
UOM: 1 * 100 µl
Leverancier: Bioss
Image Unavailable-BOSSBS-4055R-A680

Anti-PPAR alpha Ser12 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Omschrijving: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine (16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
Catalogus nummer: BOSSBS-4055R-A680
UOM: 1 * 100 µl
Leverancier: Bioss
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