U heeft gezocht op: Antilichamen

Catalogus nummer: (BOSSBS-5904R-FITC)

Leverancier: Bioss

Omschrijving: Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.

UOM: 1 * 100 µl

Sale

Catalogus nummer: (BOSSBS-2014R-A750)

Leverancier: Bioss

Omschrijving: Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis.

UOM: 1 * 100 µl

Sale

Catalogus nummer: (BOSSBS-13483R-A488)

Leverancier: Bioss

Omschrijving: Belongs to the GOLGA6 family.

UOM: 1 * 100 µl

Sale

Catalogus nummer: (BOSSBS-0679R-CY5.5)

Leverancier: Bioss

Omschrijving: Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation. Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Also promotes the degradation of normal but naturally short-lived proteins such as SGK. Protects cells from ER stress-induced apoptosis. Protects neurons from apoptosis induced by polyglutamine-expanded huntingtin (HTT) or unfolded GPR37 by promoting their degradation. Sequesters p53/TP53 in the cytoplasm and promotes its degradation, thereby negatively regulating its biological function in transcription, cell cycle regulation and apoptosis.

UOM: 1 * 100 µl

Sale

Catalogus nummer: (BOSSBS-0679R-A680)

Leverancier: Bioss

Omschrijving: Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation. Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Also promotes the degradation of normal but naturally short-lived proteins such as SGK. Protects cells from ER stress-induced apoptosis. Protects neurons from apoptosis induced by polyglutamine-expanded huntingtin (HTT) or unfolded GPR37 by promoting their degradation. Sequesters p53/TP53 in the cytoplasm and promotes its degradation, thereby negatively regulating its biological function in transcription, cell cycle regulation and apoptosis.

UOM: 1 * 100 µl

Sale

Catalogus nummer: (BOSSBS-0680R-A555)

Leverancier: Bioss

Omschrijving: When present in a hybrid receptor with INSR, binds IGF1. PubMed:12138094 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, PubMed:16831875 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin.

UOM: 1 * 100 µl

Sale

Catalogus nummer: (BOSSBS-0679R-HRP)

Leverancier: Bioss

Omschrijving: Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation. Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Also promotes the degradation of normal but naturally short-lived proteins such as SGK. Protects cells from ER stress-induced apoptosis. Protects neurons from apoptosis induced by polyglutamine-expanded huntingtin (HTT) or unfolded GPR37 by promoting their degradation. Sequesters p53/TP53 in the cytoplasm and promotes its degradation, thereby negatively regulating its biological function in transcription, cell cycle regulation and apoptosis.

UOM: 1 * 100 µl

Sale

Catalogus nummer: (BOSSBS-6092R-CY5)

Leverancier: Bioss

Omschrijving: RHOBTB1 is a member of the Rho family of the small GTPase superfamily. Is made of a GTPase domain, a proline-rich region, a tandem of 2 BTB (broad complex, tramtrack, and bric-a-brac) domains, and a conserved C-terminal region. Plays a role in small GTPase-mediated signal transduction and the organization of the actin filament system.

UOM: 1 * 100 µl

Sale

Catalogus nummer: (BOSSBS-13483R-A350)

Leverancier: Bioss

Omschrijving: Belongs to the GOLGA6 family.

UOM: 1 * 100 µl

Sale

Catalogus nummer: (BOSSBS-0679R-A750)

Leverancier: Bioss

Omschrijving: Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation. Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Also promotes the degradation of normal but naturally short-lived proteins such as SGK. Protects cells from ER stress-induced apoptosis. Protects neurons from apoptosis induced by polyglutamine-expanded huntingtin (HTT) or unfolded GPR37 by promoting their degradation. Sequesters p53/TP53 in the cytoplasm and promotes its degradation, thereby negatively regulating its biological function in transcription, cell cycle regulation and apoptosis.

UOM: 1 * 100 µl

Sale

Catalogus nummer: (BOSSBS-5904R-A680)

Leverancier: Bioss

Omschrijving: Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.

UOM: 1 * 100 µl

Sale

Catalogus nummer: (BOSSBS-5907R-CY5)

Leverancier: Bioss

Omschrijving: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).

UOM: 1 * 100 µl

Sale

Catalogus nummer: (BOSSBS-5907R-A488)

Leverancier: Bioss

Omschrijving: Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney (By similarity).

UOM: 1 * 100 µl

Sale

Catalogus nummer: (NOVUNBP1-45057)

Leverancier: Novus Biologicals

Omschrijving: The PSMA / FOLH1 / NAALADase I Antibody (GCP-04) from Novus Biologicals is a mouse monoclonal antibody to PSMA / FOLH1 / NAALADase I. This antibody reacts with human, mouse, rat, porcine. The PSMA / FOLH1 / NAALADase I Antibody (GCP-04) has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry / Immunofluorescence, Immunohistochemistry-Paraffin.

UOM: 1 * 1 EA

Sale

Catalogus nummer: (BOSSBS-6634R-A488)

Leverancier: Bioss

Omschrijving: Involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. Has only a low DNA repair activity by itself which is stimulated by RAD23B and RAD23A. Has a preference to bind DNA containing a short single-stranded segment but not to damaged oligonucleotides. This feature is proposed to be related to a dynamic sensor function: XPC can rapidly screen duplex DNA for non-hydrogen-bonded bases by forming a transient nucleoprotein intermediate complex which matures into a stable recognition complex through an intrinsic single-stranded DNA-binding activity. The XPC complex is proposed to represent the first factor bound at the sites of DNA damage and together with other core recognition factors, XPA, RPA and the TFIIH complex, is part of the pre-incision (or initial recognition) complex. The XPC complex recognizes a wide spectrum of damaged DNA characterized by distortions of the DNA helix such as single-stranded loops, mismatched bubbles or single-stranded overhangs. The orientation of XPC complex binding appears to be crucial for inducing a productive NER. XPC complex is proposed to recognize and to interact with unpaired bases on the undamaged DNA strand which is followed by recruitment of the TFIIH complex and subsequent scanning for lesions in the opposite strand in a 5'-to-3' direction by the NER machinery. Cyclobutane pyrimidine dimers (CPDs) which are formed upon UV-induced DNA damage esacpe detection by the XPC complex due to a low degree of structural perurbation. Instead they are detected by the UV-DDB complex which in turn recruits and cooperates with the XPC complex in the respective DNA repair. In vitro, the XPC:RAD23B dimer is sufficient to initiate NER; it preferentially binds to cisplatin and UV-damaged double-stranded DNA and also binds to a variety of chemically and structurally diverse DNA adducts.

UOM: 1 * 100 µl

Sale

Catalogus nummer: (BOSSBS-1027R-CY7)

Leverancier: Bioss

Omschrijving: Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity).

UOM: 1 * 100 µl

Sale