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Catalogus nummer: (ENZOALX522099C050)
Leverancier: ENZO LIFE SCIENCES
Omschrijving: Produced in CHO cells. The sequence coding for the 4 extracellular Ig-like domains of mouse LAG-3 (D1-D4) is fused to the Fc portion of mouse IgG2a (hinge-CH2-CH3).
UOM: 1 * 1 EA


Catalogus nummer: (ENZOALX804806FC100)
Leverancier: ENZO LIFE SCIENCES
Omschrijving: The lymphocyte activation gene-3 (LAG-3, CD223), a member of the immunoglobulin superfamily (IgSF) related to CD4, binds to the major histocompatibility complex (MHC) class II molecules but with higher affinity than CD4. Several alternative mRNA splice-variants of human LAG-3 have been described, two of them encoding potential secreted forms: LAG-3V1 (i.e. the D1-D2 domains of the protein, 36 kDa) and LAG-3V3 (D1-D3, 52 kDa). The longer form was detected by ELISA in the serum of healthy individuals as well as of tuberculosis patients with a favorable outcome. LAG-3 expression by T cell clones correlated with IFN-γ production, and hence soluble LAG-3 has been suggested as a serological marker of Th1 responses.
UOM: 1 * 1 EA


Catalogus nummer: (USBI125534)
Leverancier: US Biological
Omschrijving: Anti-CCND1 Mouse Polyclonal Antibody
UOM: 1 * 1 EA


Catalogus nummer: (BOSSBS-6691R-CY3)
Leverancier: Bioss
Omschrijving: Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
UOM: 1 * 100 µl


Catalogus nummer: (ENZOALX270296M001)
Leverancier: ENZO LIFE SCIENCES
Omschrijving: Inhibitor of cyclin-dependent kinases (CDKs), with selectivity for CDK1/cyclin B (IC50=55 nm), CDK2/cyclin A (IC50=35 nm), CDK2/cyclin E (IC50=150 nm), CDK4/cyclin D1 (IC50=300 nm), CDK5/p35 (IC50=65 nm) and GSK-3β (IC50=280 nm).
UOM: 1 * 1 mg


Leverancier: Cayman Chemical
Omschrijving: Purvalanol A is a potent, cell-permeable, and selective inhibitor of cyclin-dependent kinases (CDKs) with IC50 values of 4, 70, 35, 850, and 75 nM for cdc2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E, Cdk4/cyclin D1 and Cdk5-p35, respectively.

Catalogus nummer: (BOSSBS-6691R-FITC)
Leverancier: Bioss
Omschrijving: Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-2172R-A680)
Leverancier: Bioss
Omschrijving: URG4 may be involved in cell cycle progression through the regulation of cyclin D1 expression. It may participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. URG4 may play an important role in development of gastric cancer.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-2171R-CY7)
Leverancier: Bioss
Omschrijving: URG4 may be involved in cell cycle progression through the regulation of cyclin D1 expression. It may participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. URG4 may play an important role in development of gastric cancer.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-2171R-A750)
Leverancier: Bioss
Omschrijving: URG4 may be involved in cell cycle progression through the regulation of cyclin D1 expression. It may participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. URG4 may play an important role in development of gastric cancer.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-2172R-FITC)
Leverancier: Bioss
Omschrijving: URG4 may be involved in cell cycle progression through the regulation of cyclin D1 expression. It may participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. URG4 may play an important role in development of gastric cancer.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-12554R)
Leverancier: Bioss
Omschrijving: Myb-Related Protein B (MYBL2), a member of the MYB family of transcription factor genes, is a nuclear protein involved in the regulation of cell survival, proliferation, and differentiation. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-6691R-A350)
Leverancier: Bioss
Omschrijving: Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. Stimulates E2F1/TFDP1 transcriptional activity. Renders the activity of cyclin D1/CDK4 resistant to the inhibitory effects of CDKN2A/p16INK4A.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-2171R-CY5)
Leverancier: Bioss
Omschrijving: URG4 may be involved in cell cycle progression through the regulation of cyclin D1 expression. It may participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. URG4 may play an important role in development of gastric cancer.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-2171R-FITC)
Leverancier: Bioss
Omschrijving: URG4 may be involved in cell cycle progression through the regulation of cyclin D1 expression. It may participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. URG4 may play an important role in development of gastric cancer.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-2172R-CY7)
Leverancier: Bioss
Omschrijving: URG4 may be involved in cell cycle progression through the regulation of cyclin D1 expression. It may participate in the development of hepatocellular carcinoma (HCC) by promoting hepatocellular growth and survival. URG4 may play an important role in development of gastric cancer.
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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