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Image Unavailable-PRSI33-912

Anti-CDKN1C Mouse Monoclonal Antibody [clone: KIP57-1]

Catalogus nummer: (PRSI33-912)
Leverancier: ProSci Inc.
Omschrijving: Recognises a protein of 57 kDa, identified as p57Kip2. It shows no cross-reaction with p27Kip1. p57Kip2 is a potent tight-binding inhibitor of several G1 cyclin complexes, and is a negative regulator of cell proliferation. Anti-p57 has been used as an aide in identification of complete hydatidiform mole (CHM) (no nuclear labeling of cytotrophoblasts and stromal cells) from partial hydatidiform mole (PHM) in which both cytotrophoblasts and stromal cells stain. The histological differentiation of complete mole, partial mole, and hydropic spontaneous abortion is problematic. Most complete hydatidiform moles are diploid, whereas most partial moles are triploid. Ploidy studies will identify partial moles, but will not differentiate complete moles from non-molar gestations. Complete moles carry a high risk of persistent disease and choriocarcinoma, while partial moles have a very low risk. In normal placenta, many cytotrophoblast nuclei and stromal cells are labeled with this antibody. Similar findings apply to PHM and hydropic abortus tissues. Intervillous trophoblastic islands (IVTIs) demonstrate nuclear labeling in all three entities and serve as an internal control.
UOM: 1 * 1 EA

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Image Unavailable-PRSI91-583

Mouse recombinant CXCL12 (from E. coli)

Catalogus nummer: (PRSI91-583)
Leverancier: ProSci Inc.
Omschrijving: Mouse Cxcl12 is a secreted and highly conserved protein which belongs to the intercrine alpha (chemokine CxC) family.CXCL12 is widely expressed in various organs including brain, kidney, skeletal muscle, heart, liver, and lymphoid organs. Cxcl12 activates the C-X-C chemokine receptor CXCR4 to induce a rapid and transient rise in the level of intracellular calcium ions and chemotaxis. It also binds to atypical chemokine receptor ACKR3 which activates the beta-arrestin pathway and acts as a scavenger receptor for SDF-1. Cxcl12 has several critical functions during embryonic development such as B-cell lymphopoiesis, myelopoiesis in bone marrow and heart ventricular septum formation. Cxcl12 plays an important role in acting as a positive regulator of monocyte migration and a negative regulator of monocyte adhesion via the LYN kinase. It stimulates migration of monocytes and T-lymphocytes through its receptors, CXCR4 and ACKR3, and decreases monocyte adherence to surfaces coated with ICAM-1, a ligand for beta-2 integrins. SDF1A/CXCR4 signaling axis inhibits beta-2 integrin LFA-1 mediated adhesion of monocytes to ICAM-1 through LYN kinase. It also plays a protective role after myocardial infarction, induces down-regulation and internalization of ACKR3 expressed in various cells and stimulates the proliferation of bone marrow-derived b progenitor cells in the presence of IL-7 as well as growth of the stromal cell-dependent B-cell clone DW34 cells.
UOM: 1 * 1 EA
Image Unavailable-BOSSBS-6071R-A488

Anti-LRP12 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalogus nummer: (BOSSBS-6071R-A488)
Leverancier: Bioss
Omschrijving: Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6071R-A647

Anti-LRP12 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalogus nummer: (BOSSBS-6071R-A647)
Leverancier: Bioss
Omschrijving: Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2200R-CY7

Anti-APOE Rabbit Polyclonal Antibody (Cy7®)

Catalogus nummer: (BOSSBS-2200R-CY7)
Leverancier: Bioss
Omschrijving: Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2200R-CY5.5

Anti-APOE Rabbit Polyclonal Antibody (Cy5.5®)

Catalogus nummer: (BOSSBS-2200R-CY5.5)
Leverancier: Bioss
Omschrijving: Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2200R-CY3

Anti-APOE Rabbit Polyclonal Antibody (Cy3®)

Catalogus nummer: (BOSSBS-2200R-CY3)
Leverancier: Bioss
Omschrijving: Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4892R-FITC

Anti-APOE Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalogus nummer: (BOSSBS-4892R-FITC)
Leverancier: Bioss
Omschrijving: Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4892R-CY5

Anti-APOE Rabbit Polyclonal Antibody (Cy5®)

Catalogus nummer: (BOSSBS-4892R-CY5)
Leverancier: Bioss
Omschrijving: Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5038R-A680

Anti-ApoE Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalogus nummer: (BOSSBS-5038R-A680)
Leverancier: Bioss
Omschrijving: Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5038R-CY5

Anti-APOE Rabbit Polyclonal Antibody (Cy5®)

Catalogus nummer: (BOSSBS-5038R-CY5)
Leverancier: Bioss
Omschrijving: Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5038R-A750

Anti-ApoE Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalogus nummer: (BOSSBS-5038R-A750)
Leverancier: Bioss
Omschrijving: Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6071R-FITC

Anti-LRP12 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalogus nummer: (BOSSBS-6071R-FITC)
Leverancier: Bioss
Omschrijving: Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5038R-A350

Anti-APOE Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalogus nummer: (BOSSBS-5038R-A350)
Leverancier: Bioss
Omschrijving: Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5038R-CY3

Anti-APOE Rabbit Polyclonal Antibody (Cy3®)

Catalogus nummer: (BOSSBS-5038R-CY3)
Leverancier: Bioss
Omschrijving: Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5038R-HRP

Anti-APOE Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalogus nummer: (BOSSBS-5038R-HRP)
Leverancier: Bioss
Omschrijving: Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
UOM: 1 * 100 µl
Bel voor prijs
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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