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Catalogus nummer: (PRSI33-571)
Leverancier: ProSci Inc.
Omschrijving: Recognises proteins of 33, 35 and 41 kDa, which are identified as various isoforms of CD74/CLIP. Its epitope is localized in the extracellular domain of CD74. CD74/CLIP is a type II transmembrane protein which binds to the peptide binding groove of newly synthesised MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. The molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74/CLIP is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, and dendritic cells and by various types of carcinomas. It is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74/CLIP stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas and has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).
UOM: 1 * 1 EA

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Catalogus nummer: (BOSSBS-11191R-A680)
Leverancier: Bioss
Omschrijving: Myelin regulatory factor: Constitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes. Myelin regulatory factor, C-terminal: Membrane-bound part that has no transcription factor activity and remains attached to the endoplasmic reticulum membrane following cleavage. Myelin regulatory factor, N-terminal: Transcription factor that specifically activates expression of myelin genes such as MBP, MOG, MAG and PLP1 during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Specifically recognizes and binds DNA sequence 5'-CTGGYAC-3' in the regulatory regions of myelin-specific genes and directly activates their expression. Not only required during oligodendrocyte differentiation but is also required on an ongoing basis for the maintenance of expression of myelin genes and for the maintenance of a mature, viable oligodendrocyte phenotype.
UOM: 1 * 100 µl


Catalogus nummer: (USBIM9758-07B)
Leverancier: US Biological
Omschrijving: Anti-Myelin and Oligodendrocytes Mouse Monoclonal Antibody [clone: 10F184]
UOM: 1 * 100 µl


Catalogus nummer: (PRSI33-102)
Leverancier: ProSci Inc.
Omschrijving: This antibody recognises proteins of 33, 35 and 41 kDa, which are identified as various isoforms of CD74. The CD74 antibody epitope is localized in the extracellular domain of CD74. CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesised MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. The CD74 molecule plays a critical role in the presentation of peptides, by the MHC class II antigens, to CD4 positive lymphocytes. CD74 is expressed on MHC class II positive cells including B cells, a subset of activated T cells, monocytes, dendritic cells and by various types of carcinomas. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. CD74 antibody stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. CD74 antibody has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).
UOM: 1 * 1 EA

New Product


Catalogus nummer: (BOSSBS-11191R-CY3)
Leverancier: Bioss
Omschrijving: Myelin regulatory factor: Consitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes (PubMed:23966832). Myelin regulatory factor, C-terminal: Membrane-bound part that has no transcription factor activity and remains attached to the endoplasmic reticulum membrane following cleavage. Myelin regulatory factor, N-terminal: Transcription factor that specifically activates expression of myelin genes such as MBP, MOG, MAG and PLP1 during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Specifically recognizes and binds DNA sequence 5'-CTGGYAC-3' in the regulatory regions of myelin-specific genes and directly activates their expression. Not only required during oligodendrocyte differentiation but is also required on an ongoing basis for the maintenance of expression of myelin genes and for the maintenance of a mature, viable oligodendrocyte phenotype (PubMed:23966832).
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-11191R-FITC)
Leverancier: Bioss
Omschrijving: Myelin regulatory factor: Consitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes (PubMed:23966832). Myelin regulatory factor, C-terminal: Membrane-bound part that has no transcription factor activity and remains attached to the endoplasmic reticulum membrane following cleavage. Myelin regulatory factor, N-terminal: Transcription factor that specifically activates expression of myelin genes such as MBP, MOG, MAG and PLP1 during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Specifically recognizes and binds DNA sequence 5'-CTGGYAC-3' in the regulatory regions of myelin-specific genes and directly activates their expression. Not only required during oligodendrocyte differentiation but is also required on an ongoing basis for the maintenance of expression of myelin genes and for the maintenance of a mature, viable oligodendrocyte phenotype (PubMed:23966832).
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-11191R-CY5)
Leverancier: Bioss
Omschrijving: Myelin regulatory factor: Consitutes a precursor of the transcription factor. Mediates the autocatalytic cleavage that releases the Myelin regulatory factor, N-terminal component that specifically activates transcription of central nervous system (CNS) myelin genes (PubMed:23966832). Myelin regulatory factor, C-terminal: Membrane-bound part that has no transcription factor activity and remains attached to the endoplasmic reticulum membrane following cleavage. Myelin regulatory factor, N-terminal: Transcription factor that specifically activates expression of myelin genes such as MBP, MOG, MAG and PLP1 during oligodendrocyte (OL) maturation, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Specifically recognizes and binds DNA sequence 5'-CTGGYAC-3' in the regulatory regions of myelin-specific genes and directly activates their expression. Not only required during oligodendrocyte differentiation but is also required on an ongoing basis for the maintenance of expression of myelin genes and for the maintenance of a mature, viable oligodendrocyte phenotype (PubMed:23966832).
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-1000R-CY7)
Leverancier: Bioss
Omschrijving: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin.
UOM: 1 * 100 µl


Catalogus nummer: (83952-1SET-F)
Leverancier: Merck
Omschrijving: The kit contains set of brown(83951), yellow (83883), red (87448), greenish-yellow (82995), and brownish-yellow (86293) colour reference standards. The solutions are produced from three primary metal salt solutions of ferric(III) chloride, cobalt(II) chloride, and copper(II) sulfate pentahydrate, in accordance with chapter 2.2.2 ′Degree of colouration of liquids′ of the European Pharmacopoeia (Ph. Eur.).
UOM: 1 * 1 Kit


Catalogus nummer: (83951-1SET-F)
Leverancier: Merck
Omschrijving: The kit contains a set of nine brown colour reference standards (identified sequentially from B1 to B9) and a 1% hydrogen chloride solution in water. The solutions are produced from three primary metal salt solutions of ferric(III) chloride, cobalt(II) chloride, and copper(II) sulfate pentahydrate, in accordance with chapter 2.2.2 ′Degree of colouration of liquids′ of the European Pharmacopoeia (Ph. Eur.).
UOM: 1 * 1 Kit


Catalogus nummer: (ABCAAB9311-50)
Leverancier: Abcam
Omschrijving: Anti-Myelin PLP Mouse Monoclonal Antibody [clone: plpc 1]
UOM: 1 * 1 EA


Catalogus nummer: (BOSSBS-6657R-HRP)
Leverancier: Bioss
Omschrijving: Seems to be required for maintenance of peripheral nerve myelin sheath. May have a role in axon-glial interactions, possibly by interacting with the cytoplasmic domains of integral membrane proteins such as myelin-associated glycoprotein in the periaxonal regions of the Schwann cell plasma membrane. May have a role in the early phases of myelin deposition.
UOM: 1 * 100 µl


Catalogus nummer: (BSENC-1804-50)
Leverancier: Biosensis
Omschrijving: May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. Ref: uniprot.org
UOM: 1 * 50 µl


Catalogus nummer: (BOSSBS-2032R-HRP)
Leverancier: Bioss
Omschrijving: PMP2 is a small basic protein, belonging to the fatty-acid binding protein (FABP) family and is one of the major proteins of peripheral myelin. It appears to be involved in the transport of fatty acids or the metabolism of myelin lipids, and has been shown to have lipid-binding activity. PMP2 protein may have an important role in the organization of compact myelin.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-2032R-CY5)
Leverancier: Bioss
Omschrijving: PMP2 is a small basic protein, belonging to the fatty-acid binding protein (FABP) family and is one of the major proteins of peripheral myelin. It appears to be involved in the transport of fatty acids or the metabolism of myelin lipids, and has been shown to have lipid-binding activity. PMP2 protein may have an important role in the organization of compact myelin.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-2032R-A488)
Leverancier: Bioss
Omschrijving: PMP2 is a small basic protein, belonging to the fatty-acid binding protein (FABP) family and is one of the major proteins of peripheral myelin. It appears to be involved in the transport of fatty acids or the metabolism of myelin lipids, and has been shown to have lipid-binding activity. PMP2 protein may have an important role in the organization of compact myelin.
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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