U heeft gezocht op: N-Succinimidyl+N-methylcarbamate


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Omschrijving: May play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
Catalogus nummer: BOSSBS-4593R-A680
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
Catalogus nummer: BOSSBS-1856R-CY7
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Endopeptidase that degrades various components of the extracellular matrix, such as collagen type III and fibronectin. Activates progelatinase A. Involved in the matrix remodeling of blood vessels. Isoform short cleaves fibronectin and also collagen type III, but at lower rate. It has no effect on type I, II, IV and V collagen. However, upon interaction with CSPG4, it may be involved in degradation and invasion of type I collagen by melanoma cells.
Catalogus nummer: BOSSBS-1856R-CY3
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: The Annexins are a family of structurally similar proteins. Annexins bind to phospholipids and may be involved in regulation of membrane transport, membrane channel activity, and interaction of the cell membrane with the extracellular matrix. Annexin A4 (ANXA4) belongs to the annexin family of calcium dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane related events along exocytotic and endocytotic pathways. ANXA4 has 45 to 59% identity with other members of its family and shares a similar size and exon intron organization. Isolated from human placenta, ANXA4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANXA4 is almost exclusively expressed in epithelial cells.
Catalogus nummer: BOSSBS-1564R-HRP
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: PS, coated with mouse laminin. Laminin, a major structural component of basement membranes, has many varied functions that are mediated by binding to various components of the basement membrane (for example, collagen IV) and to cell-surface receptors. Laminin-coated cell culture plates have a number of applications, including the promotion of cell adhesion, proliferation and differentiation of a variety of cell types, particularly neurons, epithelial cells, myocytes and myoblasts.
Catalogus nummer: 734-0229
UOM: 1 * 5 ST
Leverancier: Corning

Omschrijving: Lindlar hydrogenation catalyst
Catalogus nummer: H36186.06
UOM: 1 * 5 g
Leverancier: Thermo Fisher Scientific


Omschrijving: Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
Catalogus nummer: BOSSBS-8510R-FITC
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Novel Cell-free Sclerostin/LRP Binding Assay Ideal for Primary Inhibitor Screens.
Catalogus nummer: ENZOENZ610030001
UOM: 1 * 1 Kit
Leverancier: ENZO LIFE SCIENCES


Omschrijving: Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin (By similarity).
Catalogus nummer: BOSSBS-0806R-A647
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Lood(II)hydroxycarbonaat, Extra Pure
Catalogus nummer: ACRO222710025
UOM: 1 * 2,5 kg
Leverancier: Thermo Fisher Scientific

MSDS


Omschrijving: Fibronectin is a soluble dimeric glycoprotein of 440 kDa, which is present in cells, extracellular matrix, and blood. This MAb reacts with the cellular as well as plasma form of fibronectin. Reportedly, after iv administration, this MAb localizes to tumor vessels where it binds to the underlying basement. Epitope recognized by this antibody is not accessible in normal tissues to the circulating MAb indicating that it can be used to specifically target tumor vessels in vivo. TV-1 is reportedly useful for delivering vasoactive agents to tumors to induce increased vascular permeability or blood flow prior to treatment with chemotherapeutic drugs or MAbs.
Catalogus nummer: BNC470029-100
UOM: 1 * 100 µl
Leverancier: Biotium


Omschrijving: Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury.
Catalogus nummer: BOSSBS-5871R-A750
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury.
Catalogus nummer: BOSSBS-5871R-A350
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury.
Catalogus nummer: BOSSBS-5871R-A488
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Recognizes a protein of 180 kDa, identified as CD11a (Leucocyte Workshop IV; Code 1524). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This MAb potently blocks LFA-1 dependent homotypic cell aggregation.
Catalogus nummer: BNCB0312-100
UOM: 1 * 100 µl
Leverancier: Biotium


Omschrijving: REG1 beta is a type I subclass member of the Reg gene family. The Reg gene family is a multigene family grouped into four subclasses, types I, II, III and IV based on the primary structures of the encoded proteins. REG1 beta highly similar to the REG1 alpha protein. The related REG1 alpha protein is associated with islet cell regeneration and diabetogenesis, and may be involved in pancreatic lithogenesis. Reg family members REG1 alpha, REGL, PAP and this gene are tandomly clustered on chromosome 2p12 and may have arisen from the same ancestral gene by gene duplication.
Catalogus nummer: BOSSBS-8498R-CY7
UOM: 1 * 100 µl
Leverancier: Bioss


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