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Image Unavailable-PRSI76-952

Anti-ABCB1 Mouse Monoclonal Antibody [clone: UIC2] (PE (Phycoerythrin))

Catalogus nummer: (PRSI76-952)
Leverancier: ProSci Inc.
Omschrijving: The UIC2 monoclonal antibody specifically reacts with CD243, a 170 kDa transmembrane protein also known as human multidrug resistant-1 (MDR-1) or P-glycoprotein (Pgp). It is an ATP binding cassette (ABC) transport and is expressed on B, T, NK cells to the exclusion of monocytes. CD243 is involved in the process that transports molecules across the cellular membranes and plays a role in multidrug resistance. The UIC2 antibody inhibits CD243 mediated efflux.
UOM: 1 * 1 EA
Product Image-786-018NC

Membranes and padding for Western protein transfers, pre-cut

Leverancier: G-Biosciences
Omschrijving: Pre-cut transfer membranes and padding for Western blot transfer procedures. Pre-cut membranes are supplied sandwiched between blotting paper padding. Simply soak the membrane in transfer buffer and assemble with the gel in a transfer cassette. Nitrocellulose (0,22 µm pore size) and PVDF (0,45 µm pore size) membranes are available.

Product Image-PRSI28-519

Anti-ANXA7 Rabbit Polyclonal Antibody

Catalogus nummer: (PRSI28-519)
Leverancier: ProSci Inc.
Omschrijving: ANXA7 is a member of the annexin family of calcium-dependent phospholipid binding proteins. The Annexin VII gene contains 14 exons and spans approximately 34 kb of DNA. An alternatively spliced cassette exon results in two mRNA transcripts of 2.0 and 2.4 kb which are predicted to generate two protein isoforms differing in their N-terminal domain. The alternative splicing event is tissue specific and the mRNA containing the cassette exon is prevalent in brain, heart and skeletal muscle. The transcripts also differ in their 3'-non coding regions by the use of two alternative poly (A) signals. The selection of poly (A) signals is independent of the mRNA splicing pattern. Annexin VII encodes a protein with a molecular weight of approximately 51 kDa with a unique, highly hydrophobic N-terminal domain of 167 amino acids and a conserved C-terminal region of 299 amino acids. The latter domain is composed of alternating hydrophobic and hydrophilic segments. Structural analysis of the protein suggests that Annexin VII is a membrane binding protein with diverse properties including voltage-sensitive calcium channel activity, ion selectivity and membrane fusion.
UOM: 1 * 1 EA
Product Image-PRSI25-880

Anti-TAP1 Rabbit Polyclonal Antibody

Catalogus nummer: (PRSI25-880)
Leverancier: ProSci Inc.
Omschrijving: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). TAP1 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. TAP1 is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble.The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is involved in the pumping of degraded cytosolic peptides across the endoplasmic reticulum into the membrane-bound compartment where class I molecules assemble. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM: 1 * 1 EA
Product Image-PRSI25-886

Anti-ABCB8 Rabbit Polyclonal Antibody

Catalogus nummer: (PRSI25-886)
Leverancier: ProSci Inc.
Omschrijving: The membrane-associated protein ABCB8 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). ABCB8 is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.
UOM: 1 * 1 EA
Product Image-BSBTPB9971

Anti-ABCB10 Rabbit Polyclonal Antibody

Catalogus nummer: (BSBTPB9971)
Leverancier: Boster Bio
Omschrijving: ABCB10, also known as M-ABC2, is expressed as a 60-kD nonglycosylated mitochondrial membrane protein. This ABCB10 gene is mapped to 1q42.13. The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. And ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown.
UOM: 1 * 1 EA
Product Image-GAINPRF242C1-0.5WH

Xylene-Resistant Thermal Transfer Labels for Paraffin Wax Blocks

Leverancier: GA
Omschrijving: These labels are intended for hard-to-stick surfaces, including paraffin wax, PTFE, Perfluoroalkoxy (PFA), and Parchment paper. These thermal transfer printable labels are chemical-resistant, perfect for labeling paraffin-embedded tissue cassettes used in histology applications.

Product Image-PRSI56-913

Anti-ABCC12 Rabbit Polyclonal Antibody

Catalogus nummer: (PRSI56-913)
Leverancier: ProSci Inc.
Omschrijving: This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer.
UOM: 1 * 400 µl
Image Unavailable-PRSI76-953

Anti-ABCB1 Mouse Monoclonal Antibody [clone: UIC2] (PE (Phycoerythrin))

Catalogus nummer: (PRSI76-953)
Leverancier: ProSci Inc.
Omschrijving: The UIC2 monoclonal antibody specifically reacts with CD243, a 170 kDa transmembrane protein also known as human multidrug resistant-1 (MDR-1) or P-glycoprotein (Pgp). It is an ATP binding cassette (ABC) transport and is expressed on B, T, NK cells to the exclusion of monocytes. CD243 is involved in the process that transports molecules across the cellular membranes and plays a role in multidrug resistance. The UIC2 antibody inhibits CD243 mediated efflux.
UOM: 1 * 1 EA
Product Image-216-1629

Process wafer carriers, 200 mm

Leverancier: ENTEGRIS
Omschrijving: PFA, natural.

Product Image-PRSI56-604

Anti-ABCG4 Rabbit Polyclonal Antibody

Catalogus nummer: (PRSI56-604)
Leverancier: ProSci Inc.
Omschrijving: The protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily and is expressed predominantly in liver tissue. The function has not yet been determined but may involve cholesterol transport. Alternate splice variants have been described but their full length sequences have not been determined.
UOM: 1 * 400 µl
Product Image-SARTVF05H1

Ultrafiltration units, Vivaflow 50R

Leverancier: Sartorius
Omschrijving: For 0,1 to 1000 ml, Hydrosart® membrane. Vivaflow 50R is a ready to use and reusable laboratory crossflow cassette for applications like cell culture supernatant concentration, virus concentration and water sample concentration. The thin channel, flip flow recirculation path of the modules provides high crossflow velocities with minimum pump speed requirements. A single module with 50 cm² active membrane area typically concentrates 250 ml by a factor of 20 in less than 30 min.

Image Unavailable-PRSI92-176

Human recombinant ABCB5 (from E. coli)

Catalogus nummer: (PRSI92-176)
Leverancier: ProSci Inc.
Omschrijving: ATP-binding cassette sub-family B member 5(ABCB5) is a plasma membrane-spanning protein. ABCB5 is principally expressed in physiological skin and human malignant melanoma. ABCB5 has been suggested to regulate skin progenitor cell fusion and mediate chemotherapeutic drug resistance in stem-like tumour cell subpopulations in human malignant melanoma. It is commonly over-expressed on circulating melanoma tumour cells. Furthermore, the ABCB5+ melanoma- initiating cells were demonstrated to express FLT1 (VEGFR1) receptor tyrosine kinase which was functionally required for efficient xenograft tumour formation, as demonstrated by shRNA knockdown experiments.
UOM: 1 * 1 EA
Product Image-PRSI48-673

Anti-ABCB1 Rabbit Polyclonal Antibody

Catalogus nummer: (PRSI48-673)
Leverancier: ProSci Inc.
Omschrijving: ATP-Binding Cassette Sub-Family B Member 1 (ABCB1, also named P-glycoprotein) is a plasma membrane-associated multidrug transporter that utilizes the energy of ATP hydrolysis to pump toxic xenobiotics out of cells. Unique features of ABCB1 are its very broad substrate specificity and its basal ATPase activity in the absence of transport substrates. Human ABCB1 plays an important role in absorption, distribution, metabolism, excretion and toxicity of pharmacologically relevant drugs. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anti-cancer drugs. This protein also functions as a transporter across the blood-brain barrier.
UOM: 1 * 1 EA
Product Image-PRSI55-056

Anti-ABCC10 Rabbit Polyclonal Antibody

Catalogus nummer: (PRSI55-056)
Leverancier: ProSci Inc.
Omschrijving: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This ABC full-transporter is a member of the MRP subfamily which is involved in multi-drug resistance. Multiple transcript variants encoding different isoforms have been found for this gene.
UOM: 1 * 400 µl
Product Image-631-0588

Paraffin embedding centres, basic, MPS/P1

Leverancier: Slee
Omschrijving: The MPS/P1 is a complete paraffin dispensing unit including a 3,8 litre paraffin container, a heated working area and a cold spot. The ergonomically elevated heated working area is illuminated with LED light and allows comfortable processing of specimen. All functions of the unit are controlled by an intuitive control panel. Two heated trays provide a pre-warming capacity of 80 cassettes and 200 embedding moulds. Manual lever and foot switch for the paraffin dispenser and ergonomic hand rest.

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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