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Image Unavailable-BOSSBS-3019R-CY5

Anti-EIF4EBP1 Rabbit Polyclonal Antibody (Cy5®)

Catalogus nummer: (BOSSBS-3019R-CY5)
Leverancier: Bioss
Omschrijving: Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-5337R-CY3

Anti-EIF4EBP1 Rabbit Polyclonal Antibody (Cy3®)

Catalogus nummer: (BOSSBS-5337R-CY3)
Leverancier: Bioss
Omschrijving: Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3018R-A488

Anti-EIF4EBP1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalogus nummer: (BOSSBS-3018R-A488)
Leverancier: Bioss
Omschrijving: Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
UOM: 1 * 100 µl
Image Unavailable-ENZOADI905759100

Anti-GSK3A Mouse Monoclonal Antibody

Catalogus nummer: (ENZOADI905759100)
Leverancier: ENZO LIFE SCIENCES
Omschrijving: Glycogen Synthase Kinase 3 (GSK3) exists in two isoforms, alpha and beta (GSK3α, and GSK3β). GSK3 is an active kinase that becomes phosphorylated by PKB/akt upon growth factor stimulation. Phosphorylation of GSK3α at serine 21 or GSK3β at serine 9, respectively, leads to inhibition of kinase activity of the GSK3.
UOM: 1 * 1 EA
Image Unavailable-BOSSBS-4308R-A647

Anti-ERN1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalogus nummer: (BOSSBS-4308R-A647)
Leverancier: Bioss
Omschrijving: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8680R-A680

Anti-IRE1a Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalogus nummer: (BOSSBS-8680R-A680)
Leverancier: Bioss
Omschrijving: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2509R-CY3

Anti-AIMP2 Rabbit Polyclonal Antibody (Cy3®)

Catalogus nummer: (BOSSBS-2509R-CY3)
Leverancier: Bioss
Omschrijving: Required for assembly and stability of the aminoacyl-tRNA synthase complex. Mediates ubiquitination and degradation of FUBP1, a transcriptional activator of MYC, leading to MYC down-regulation which is required for aveolar type II cell differentiation. Blocks MDM2-mediated ubiquitination and degradation of p53/TP53. Functions as a proapoptotic factor.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0127M-A647

Anti-BAX Mouse Polyclonal Antibody (Alexa Fluor® 647)

Catalogus nummer: (BOSSBS-0127M-A647)
Leverancier: Bioss
Omschrijving: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0127M-CY7

Anti-BAX Mouse Polyclonal Antibody (Cy7®)

Catalogus nummer: (BOSSBS-0127M-CY7)
Leverancier: Bioss
Omschrijving: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0127M-HRP

Anti-BAX Mouse Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalogus nummer: (BOSSBS-0127M-HRP)
Leverancier: Bioss
Omschrijving: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0127R-A350

Anti-BAX Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalogus nummer: (BOSSBS-0127R-A350)
Leverancier: Bioss
Omschrijving: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0127R-A680

Anti-Bax Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalogus nummer: (BOSSBS-0127R-A680)
Leverancier: Bioss
Omschrijving: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3019R-A750

Anti-e4EBP1 Thr37 + Thr46 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalogus nummer: (BOSSBS-3019R-A750)
Leverancier: Bioss
Omschrijving: Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3018R-A680

Anti-e4EBP1 Ser65 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalogus nummer: (BOSSBS-3018R-A680)
Leverancier: Bioss
Omschrijving: Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6393R

Anti-PLK4 Rabbit Polyclonal Antibody

Catalogus nummer: (BOSSBS-6393R)
Leverancier: Bioss
Omschrijving: Serine/threonine-protein kinase that plays a central role in centriole duplication. Able to trigger procentriole formation on the surface of the parental centriole cylinder, leading to the recruitment of centriole biogenesis proteins such as SASS6, CENPJ/CPAP, CP110, CEP135 and gamma-tubulin. When overexpressed, it is able to induce centrosome amplification through the simultaneous generation of multiple procentrioles adjoining each parental centriole during S phase. Its central role in centriole replication suggests a posible role in tumorigenesis, centrosome aberrations being frequently observed in tumors. Also involved in trophoblast differentiation by phosphorylating HAND1, leading to disrupt the interaction between HAND1 and MDFIC and activate HAND1. Phosphorylates CDC25C and CHEK2/CHK2.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0164R-CY3

Anti-BACE Rabbit Polyclonal Antibody (Cy3®)

Catalogus nummer: (BOSSBS-0164R-CY3)
Leverancier: Bioss
Omschrijving: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
UOM: 1 * 100 µl
Bel voor prijs
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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