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Catalogus nummer: (BOSSBS-11204R-A680)
Leverancier: Bioss
Omschrijving: Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.
UOM: 1 * 100 µl


Leverancier: Brady
Omschrijving: Raised panel adhesive-taped polyester (B-593) labels are designed for patch panel identification, external push-buttons, switches and internal connection points.

Catalogus nummer: (BOSSBS-3872R-CY5.5)
Leverancier: Bioss
Omschrijving: Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.
UOM: 1 * 100 µl


Catalogus nummer: (471-1256)
Leverancier: VWR Collection
Omschrijving: Freezers, Ultralage temperatuur, Vergrendelbare hoofdschakelaar
UOM: 1 * 1 ST


Catalogus nummer: (BOSSBS-3872R-A750)
Leverancier: Bioss
Omschrijving: Transcriptional activator or repressor which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence 5'-[AT]GATA[AG]-3' within regulatory regions of globin genes and of other genes expressed in erythroid cells.
UOM: 1 * 100 µl


Leverancier: Brady
Omschrijving: Deze mini-kabelvergrendelingen zijn perfect voor gebruik op ontkoppelingsschakelaars, kleine schuifafsluiters en meer.

Catalogus nummer: (BOSSBS-5708R-A680)
Leverancier: Bioss
Omschrijving: SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as repression of MYOD1-stimulated differentiation, regulation of the control switch for exiting the cell cycle and entering differentiation, repression by the PML-RARA fusion protein, BMP-induced repression, repression of switch recombination to IgA and regulation of telomere length. Component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-5708R-A750)
Leverancier: Bioss
Omschrijving: SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as repression of MYOD1-stimulated differentiation, regulation of the control switch for exiting the cell cycle and entering differentiation, repression by the PML-RARA fusion protein, BMP-induced repression, repression of switch recombination to IgA and regulation of telomere length. Component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus.
UOM: 1 * 100 µl


Leverancier: Brady
Omschrijving: Low voltage NV fuse rails with symbols "Do Not Switch" and "Warning Electricity".

Leverancier: VWR Collection
Omschrijving: Externe temperatuursondes voor gebruik van een circulatiepomp met een koelmachine. Maakt het mogelijk om bedieningspunten vanuit een koelmachine naar een externe locatie te schakelen. Compenseert het warmteverlies via de leidingen tussen de circulatiepomp en het controlepunt. Platina RTD-sensor met roestvrijstalen mantel. Rubberen koppeling met 25,4 mm Ø, verbindt mantel met flexibele kabel. De sondekabel eindigt in een vrouwelijke DB9-stekker.

Catalogus nummer: (BOSSBS-1286R-A555)
Leverancier: Bioss
Omschrijving: Mediates B-cell proliferation in the absence of co-stimulus as well as IgE production in the presence of IL-4. Involved in immunoglobulin class switching. Release of soluble CD4L from platelets is partially regulated by GP IIb/IIIa, actin polymerization, and an matrix metalloproteinases (MMP) inhibitor-sensitive pathway.
UOM: 1 * 100 µl


Catalogus nummer: (HICH99341)
Leverancier: Avantor
Omschrijving: Prevail™ HPLC columns exhibit long column lifetime in both highly aqueous and highly organic mobile phases. All phases, apart from Prevail™ Carbohydrate ES are silica-based. The stability of these phases is such that a single column can be switched between highly aqueous for analysis of highly polar analytes and highly organic for strong retention of hydrophobic analytes.
UOM: 1 * 1 ST


Catalogus nummer: (BOSSBS-12520R-A647)
Leverancier: Bioss
Omschrijving: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity). Binds DNA non-specifically.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-5708R-CY5)
Leverancier: Bioss
Omschrijving: SUV39H1 is targeted to histone H3 via its interaction with RB1 and is involved in many processes, such as repression of MYOD1-stimulated differentiation, regulation of the control switch for exiting the cell cycle and entering differentiation, repression by the PML-RARA fusion protein, BMP-induced repression, repression of switch recombination to IgA and regulation of telomere length. Component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone-modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus.
UOM: 1 * 100 µl


Leverancier: Brady
Omschrijving: These breaker blockers are ideal for locking out oversized and irregularly shaped switches.

Catalogus nummer: (BOSSBS-2583R-CY3)
Leverancier: Bioss
Omschrijving: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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