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Omschrijving: Lubricin, also designated proteoglycan-4 or megakaryocyte stimulating factor, is important for boundary lubrication within articulating joints. It is a disulfide-linked homodimer (between Cysteine 1146 and Cysteine 1403) that is essential for protein cleavage. Lubricin inhibits synovial cell adhesion to the cartilage surface, but also prevents the deposition of proteins from synovial fluid onto cartilage. Lubricin is highly expressed in cartilage, liver and synovial tissue. Defects in the gene encoding for lubricin can cause Jakobs syndrome, also designated camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP). CACP is an autosomal recessive disorder characterised by joint failure associated with noninflammatory synoviocyte hyperplasia and subinitimal fibrosis of the synovial capsule. Lubricin undergoes different levels of glycosylation and may be detected at varying molecular weights.
Catalogus nummer: BOSSBS-11175R-A750
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
Catalogus nummer: BOSSBS-0156R-A555
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
Catalogus nummer: BOSSBS-0156R-CY5
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: CRP2BP is a 782 amino acid protein encoded by the human gene CSRP2BP. CRP2BP specifically interacts with the double LIM domain protein CRP2. The LIM domain is a conserved cysteine and histidine-containing structural module of two tandemly arranged zinc fingers. It has been identified in single or multiple copies in a variety of regulatory proteins, either in combination with defined functional domains, like homeodomains, or alone, like in the CRP family of LIM proteins. Members of the cysteine- and glycine-rich protein family (CRP1, CRP2 and CRP3) contain two zinc-binding LIM domains, LIM1 (amino-terminal) and LIM2 (carboxyl-terminal), and are implicated in diverse cellular processes linked to differentiation, growth control and pathogenesis. Although present in cytoplasm, CRP2BP is mainly a ubiquitously expressed nuclear protein, with highest expression in skeletal muscle and heart.
Catalogus nummer: BOSSBS-12947R-A555
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: CRELD1 is a protein composed of Epidermal growth factor-like repeats, which represent a group of cysteine-rich domains that mediate interactions between proteins of diverse function. Such domains are found in proteins that are either completely secreted or have transmembrane regions that link the protein to the cell surface.
Catalogus nummer: BOSSBS-8184R
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: L(+)-Cysteine hydrochloride monohydrate
Catalogus nummer: SERA17769.01
UOM: 1 * 25 g
Leverancier: Serva


Omschrijving: Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In the brain and peripheral nervous system, NO displays many properties of a neurotransmitter. Probably has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such SRR.
Catalogus nummer: BOSSBS-0156R-HRP
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Anti-SERPIND1 Goat Polyclonal Antibody (Biotin)
Catalogus nummer: USBIS1000-77Y
UOM: 1 * 1 EA
Leverancier: US Biological


Omschrijving: Anti-SERPINB8 Sheep Polyclonal Antibody
Catalogus nummer: USBIS1000-77X
UOM: 1 * 1 EA
Leverancier: US Biological


Omschrijving: Lubricin, also designated proteoglycan-4 or megakaryocyte stimulating factor, is important for boundary lubrication within articulating joints. It is a disulfide-linked homodimer (between Cysteine 1146 and Cysteine 1403) that is essential for protein cleavage. Lubricin inhibits synovial cell adhesion to the cartilage surface, but also prevents the deposition of proteins from synovial fluid onto cartilage. Lubricin is highly expressed in cartilage, liver and synovial tissue. Defects in the gene encoding for lubricin can cause Jakobs syndrome, also designated camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP). CACP is an autosomal recessive disorder characterized by joint failure associated with noninflammatory synoviocyte hyperplasia and subinitimal fibrosis of the synovial capsule. Lubricin undergoes different levels of glycosylation and may be detected at varying molecular weights.
Catalogus nummer: BOSSBS-11175R-A488
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: Lubricin, also designated proteoglycan-4 or megakaryocyte stimulating factor, is important for boundary lubrication within articulating joints. It is a disulfide-linked homodimer (between Cysteine 1146 and Cysteine 1403) that is essential for protein cleavage. Lubricin inhibits synovial cell adhesion to the cartilage surface, but also prevents the deposition of proteins from synovial fluid onto cartilage. Lubricin is highly expressed in cartilage, liver and synovial tissue. Defects in the gene encoding for lubricin can cause Jakobs syndrome, also designated camptodactyly-arthropathy-coxa vara-pericarditis syndrome (CACP). CACP is an autosomal recessive disorder characterized by joint failure associated with noninflammatory synoviocyte hyperplasia and subinitimal fibrosis of the synovial capsule. Lubricin undergoes different levels of glycosylation and may be detected at varying molecular weights.
Catalogus nummer: BOSSBS-11175R-FITC
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: L(+)-Cysteine hydrochloride monohydrate
Catalogus nummer: EDQMC3290000
UOM: 1 * 100 mg
Leverancier: EDQM


Omschrijving: L(+)-Cysteine hydrochloride monohydrate
Catalogus nummer: ROTHT203.2
UOM: 1 * 100 g
Leverancier: Roth Carl


Omschrijving: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Catalogus nummer: BOSSBS-1351R-CY3
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen Signalling.
Catalogus nummer: BOSSBS-11277R-A680
UOM: 1 * 100 µl
Leverancier: Bioss


Omschrijving: DnaJ-like proteins interact with HSP 70 molecular chaperones and function to facilitate protein folding and mitochondrial protein import. HSP 40-4, also known as HDJ2, is the human DnaJ homolog that functions as a co-chaperone with a cysteine-rich zinc finger domain. The cellular redox enzyme thioredoxin interacts with HSP 40-4, and oxidation and reduction reversibly regulate HSP 40-4 function in response to the changing redox states of the cell. The zinc finger domain of HSP 40-4 may act as a redox sensor of chaperone-mediated protein-folding machinery, since HSP 40-4 inactivation leads to the oxidation of cysteine thiols and a simultaneous release of coordinated zinc. Loss of the HSP 40-4 protein may be linked to severe defects in spermatogenesis that involve aberrant androgen signaling.
Catalogus nummer: BOSSBS-11277R
UOM: 1 * 100 µl
Leverancier: Bioss