U heeft gezocht op: Iron+disilicide

Catalogus nummer: (BOSSBS-11788R-A647)

Leverancier: Bioss

Omschrijving: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-11788R-FITC)

Leverancier: Bioss

Omschrijving: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

UOM: 1 * 100 µl

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Leverancier: Thermo Fisher Scientific

Omschrijving: Potassium trioxalatoferrate(III) trihydrate

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Catalogus nummer: (BOSSBS-6053R-CY5.5)

Leverancier: Bioss

Omschrijving: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-11788R-A750)

Leverancier: Bioss

Omschrijving: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-11788R-A680)

Leverancier: Bioss

Omschrijving: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

UOM: 1 * 100 µl

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Leverancier: ENZO LIFE SCIENCES

Omschrijving: Heme Oxygenase-1 (HO-1) also known as Hsp32, is the inducible isoform of heme oxygenase that catalyzes the NADPH, oxygen, and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, ferrous iron and biliverdin which is rapidly reduced to bilirubin. These products of the HO reaction have important physiological effects: carbon monoxide is a potent vasodilator and has been implicated to be a physiological regulator of cGMP and vascular tone; biliverdin and its product bilirubin are potent antioxidants; "free" iron increases oxidative stress and regulates the expression of many mRNAs (e.g., DCT-1, ferritin and transferring receptor) by affecting the conformation of iron regulatory protein (IRP)-1 and its binding to iron regulatory elements (IREs) in the 5'- or 3'- UTRs of the mRNAs. To date, three identified heme oxygenase isoforms are part of the HO system that catalyze heme into biliverdin and carbon monoxide. These are inducible HO-1 or Hsp32, constitutive HO-2 that is abundant in the brain and testis, and HO-3 which is related to HO-2 but is the product of a different gene. The HO system is the rate-limiting step in heme degradation and HO activity decreases the levels of heme which is a well known potent catalyst of lipid peroxidation and oxygen radical formation.

Catalogus nummer: (BOSSBS-11788R-A350)

Leverancier: Bioss

Omschrijving: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-7157R-HRP)

Leverancier: Bioss

Omschrijving: Mitoferrin 2, also known as MRS3/4 (mitochondrial RNA-splicing protein 3/4 homolog), mitochondrial iron transporter 2, NPD016, MRS4L or SLC25A28 (solute carrier family 25 member 28), is a 364 amino acid multi-pass membrane protein of the mitochondrial inner membrane that mediates iron uptake. Mitoferrin 2 is thought to play a role in heme synthesis of hemoproteins and iron-sulfur cluster assembly. Ubiquitously expressed, Mitoferrin 2 is found at high levels in skeletal muscle, heart, placenta, kidney, lung, liver, brain and pancreas. Mitoferrin 2 is a member of the mitochondrial carrier family and undergoes alternative splicing events to produce four isoforms. Mitoferrin 2 contains three solcar repeats and is encoded by a gene that maps to human chromosome 10q24.2.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-0988R-CY5.5)

Leverancier: Bioss

Omschrijving: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-8468R-A680)

Leverancier: Bioss

Omschrijving: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognises and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-8468R-A750)

Leverancier: Bioss

Omschrijving: Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in iron homeostasis by promoting the ubiquitination and subsequent degradation of IREB2/IRP2. Upon high iron and oxygen level, it specifically recognises and binds IREB2/IRP2, promoting its ubiquitination and degradation by the proteasome. Promotes ubiquitination and subsequent degradation of DCTN1/p150-glued.

UOM: 1 * 100 µl

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Catalogus nummer: (241-0104)

Leverancier: VWR Collection

Omschrijving: PU-gecoate gietijzeren voet, hoogwaardige stalen staaf 500×12 mm.

UOM: 1 * 1 ST

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Catalogus nummer: (BOSSBS-6053R)

Leverancier: Bioss

Omschrijving: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-11788R-CY7)

Leverancier: Bioss

Omschrijving: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).

UOM: 1 * 100 µl

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Catalogus nummer: (USBI128577)

Leverancier: US Biological

Omschrijving: Anti-IREB2 Mouse Polyclonal Antibody

UOM: 1 * 1 EA

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