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Catalogus nummer: (241-0104)
Leverancier: VWR Collection
Omschrijving: PU-gecoate gietijzeren voet, hoogwaardige stalen staaf 500×12 mm.
UOM: 1 * 1 ST


Catalogus nummer: (BOSSBS-11788R-A350)
Leverancier: Bioss
Omschrijving: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-0988R-FITC)
Leverancier: Bioss
Omschrijving: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.
UOM: 1 * 100 µl


Leverancier: ENZO LIFE SCIENCES
Omschrijving: Heme Oxygenase-1 (HO-1) also known as Hsp32, is the inducible isoform of heme oxygenase that catalyzes the NADPH, oxygen, and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, ferrous iron and biliverdin which is rapidly reduced to bilirubin. These products of the HO reaction have important physiological effects: carbon monoxide is a potent vasodilator and has been implicated to be a physiological regulator of cGMP and vascular tone; biliverdin and its product bilirubin are potent antioxidants; "free" iron increases oxidative stress and regulates the expression of many mRNAs (e.g., DCT-1, ferritin and transferring receptor) by affecting the conformation of iron regulatory protein (IRP)-1 and its binding to iron regulatory elements (IREs) in the 5'- or 3'- UTRs of the mRNAs. To date, three identified heme oxygenase isoforms are part of the HO system that catalyze heme into biliverdin and carbon monoxide. These are inducible HO-1 or Hsp32, constitutive HO-2 that is abundant in the brain and testis, and HO-3 which is related to HO-2 but is the product of a different gene. The HO system is the rate-limiting step in heme degradation and HO activity decreases the levels of heme which is a well known potent catalyst of lipid peroxidation and oxygen radical formation.

Catalogus nummer: (BOSSBS-12565R-A647)
Leverancier: Bioss
Omschrijving: ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumor DNA. Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases.
UOM: 1 * 100 µl


Leverancier: Thermo Fisher Scientific
Omschrijving: For grain mounts, XRD and microprobe standards, identification of unknown minerals
Hardness: 6-6.5
Catalogus nummer: (BOSSBS-15075R-A350)
Leverancier: Bioss
Omschrijving: Belonging to the CAF17 subfamily of the gcvT family, C1orf69 is a 356 amino acid mitochondrial protein that is required for normal heme synthesis. Heme synthesis is dependent upon receiving iron through iron sulfur (Fe-S) cluster biogenesis proteins such as C1orf69, which is specifically thought to assemble Fe-S clusters for mitochondrial aconitase and lipoate synthase. In zebrafish, deficiency of C1orf69 causes anemia. The gene encoding C1orf69 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-15075R-A555)
Leverancier: Bioss
Omschrijving: Belonging to the CAF17 subfamily of the gcvT family, C1orf69 is a 356 amino acid mitochondrial protein that is required for normal heme synthesis. Heme synthesis is dependent upon receiving iron through iron sulfur (Fe-S) cluster biogenesis proteins such as C1orf69, which is specifically thought to assemble Fe-S clusters for mitochondrial aconitase and lipoate synthase. In zebrafish, deficiency of C1orf69 causes anemia. The gene encoding C1orf69 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-15075R-CY5)
Leverancier: Bioss
Omschrijving: Belonging to the CAF17 subfamily of the gcvT family, C1orf69 is a 356 amino acid mitochondrial protein that is required for normal heme synthesis. Heme synthesis is dependent upon receiving iron through iron sulfur (Fe-S) cluster biogenesis proteins such as C1orf69, which is specifically thought to assemble Fe-S clusters for mitochondrial aconitase and lipoate synthase. In zebrafish, deficiency of C1orf69 causes anemia. The gene encoding C1orf69 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-11788R-A555)
Leverancier: Bioss
Omschrijving: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-6053R-A647)
Leverancier: Bioss
Omschrijving: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-6053R-A555)
Leverancier: Bioss
Omschrijving: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-6053R-A750)
Leverancier: Bioss
Omschrijving: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-15417R-CY3)
Leverancier: Bioss
Omschrijving: ISCA1 is a mitochondrial protein involved in the biogenesis and assembly of iron-sulfur clusters, which play a role in electron-transfer reactions.
UOM: 1 * 100 µl


Catalogus nummer: (241-0045)
Leverancier: VWR Collection
Omschrijving: Voet uit PU gecoat gietijzer (200×450 mm), stalen staaf (500×12 mm), staafkoppelstuk en houder voor vier trechters.
UOM: 1 * 1 ST


Catalogus nummer: (BOSSBS-15417R-A555)
Leverancier: Bioss
Omschrijving: ISCA1 is a mitochondrial protein involved in the biogenesis and assembly of iron-sulfur clusters, which play a role in electron-transfer reactions.
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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