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Catalogus nummer: (BOSSBS-12335R-A555)
Leverancier: Bioss
Omschrijving: The features of hemochromatosis include cirrhosis of the liver, diabetes, hypermelanotic pigmentation of the skin, and heart failure. Since hemochromatosis is a relatively easily treated disorder if diagnosed, this is a form of preventable cancer. The HFE protein, which is defective in hereditary hemo-chromatosis, normally is expressed in crypt enterocytes of the duodenum where it has a unique, predominantly intracellular localization. In placenta, the HFE protein co-localizes with and forms a stable association with the transferrin receptor (TfR), providing a link between the HFE protein and iron transport. Immunocytochemistry shows that the HFE protein and TfR both are expressed in the crypt enterocytes. Western blots show that, as is the case in human placenta, the HFE protein in crypt enterocytes is physically associated with the TfR and with β2-microglobulin. It is proposed that HFE has two mutually exclusive activities in cells: inhibition of uptake or inhibition of release of iron and that the balance between serum transferrin saturation and serum transferrin-receptor concentrations determines which of these functions predominates. The gene which encodes HFE maps to human chromosome 6p21.3.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-12335R-FITC)
Leverancier: Bioss
Omschrijving: The features of hemochromatosis include cirrhosis of the liver, diabetes, hypermelanotic pigmentation of the skin, and heart failure. Since hemochromatosis is a relatively easily treated disorder if diagnosed, this is a form of preventable cancer. The HFE protein, which is defective in hereditary hemo-chromatosis, normally is expressed in crypt enterocytes of the duodenum where it has a unique, predominantly intracellular localization. In placenta, the HFE protein co-localizes with and forms a stable association with the transferrin receptor (TfR), providing a link between the HFE protein and iron transport. Immunocytochemistry shows that the HFE protein and TfR both are expressed in the crypt enterocytes. Western blots show that, as is the case in human placenta, the HFE protein in crypt enterocytes is physically associated with the TfR and with β2-microglobulin. It is proposed that HFE has two mutually exclusive activities in cells: inhibition of uptake or inhibition of release of iron and that the balance between serum transferrin saturation and serum transferrin-receptor concentrations determines which of these functions predominates. The gene which encodes HFE maps to human chromosome 6p21.3.
UOM: 1 * 100 µl


Catalogus nummer: (88398.080)
Leverancier: VWR Chemicals
Omschrijving: CRM's - secondary reference materials intended for standardisation of volumetric solutions in accordance with the Pharmacopoeia (Ph. Eur. and USP). These volumetric standards are prepared from high purity salts. Certified mass fraction is determined by classical analysis according to ISO/IEC 17025. Homogeneity and stability studies have been performed according to the requirements of ISO 17034 and ISO Guide 35. All volumetric standards are traceable to SI (NIST or BAM).
UOM: 1 * 80 g

Leverancier: Spectrum Chemical
Omschrijving: Ferrous Fumarate, USP is a mineral supplement.

Catalogus nummer: (BOSSBS-12335R)
Leverancier: Bioss
Omschrijving: The features of hemochromatosis include cirrhosis of the liver, diabetes, hypermelanotic pigmentation of the skin, and heart failure. Since hemochromatosis is a relatively easily treated disorder if diagnosed, this is a form of preventable cancer. The HFE protein, which is defective in hereditary hemo-chromatosis, normally is expressed in crypt enterocytes of the duodenum where it has a unique, predominantly intracellular localization. In placenta, the HFE protein co-localizes with and forms a stable association with the transferrin receptor (TfR), providing a link between the HFE protein and iron transport. Immunocytochemistry shows that the HFE protein and TfR both are expressed in the crypt enterocytes. Western blots show that, as is the case in human placenta, the HFE protein in crypt enterocytes is physically associated with the TfR and with β2-microglobulin. It is proposed that HFE has two mutually exclusive activities in cells: inhibition of uptake or inhibition of release of iron and that the balance between serum transferrin saturation and serum transferrin-receptor concentrations determines which of these functions predominates. The gene which encodes HFE maps to human chromosome 6p21.3.
UOM: 1 * 100 µl


Leverancier: USBECK Laborgeräte
Omschrijving: Vernikkeld messing met gietijzeren voet.

Catalogus nummer: (BOSSBS-7817R-A488)
Leverancier: Bioss
Omschrijving: Implicated in the regulation of centrosome duplication (By similarity). Component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for maturation of extramitochondrial Fe/S proteins. May bind and transfer 2 labile 4Fe-4S clusters to target apoproteins.
UOM: 1 * 100 µl


Catalogus nummer: (555680ZA)
Leverancier: VWR Chemicals
Omschrijving: Kant-en-klare voedingsbodems voor microbiologische testen in de levensmiddelenindustrie, water- en milieuinspectie en de farmaceutische industrie. Alle voedingsbodems worden vervaardigd met geselecteerde gedehydrateerde bodems, en voldoen aan diverse normen. Alle bodems worden geproduceerd op basis van de nieuwste technologie en worden onderworpen aan de strengste kwaliteitscontroles die worden uitgevoerd door gekwalificeerde microbiologen.
UOM: 1 * 10 ST

Catalogus nummer: (USBI037099-PE)
Leverancier: US Biological
Omschrijving: Anti-IREB2 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM: 1 * 200 µl


Leverancier: VWR Chemicals
Omschrijving: Een reeks voedingsbodems conform ISO-normen en de internationale geharmoniseerde farmacopees. Al onze media zijn, zoals u zou verwachten, vervaardigd met hoogwaardige grondstoffen en worden onderworpen aan strikte kwaliteitscontroles in een productieomgeving die voldoet aan richtlijnen van beproefde fabricagemethoden. Grondstoffen worden geselecteerd in overeenstemming met de vereiste normen. Gedehydrateerde voedingsbodems moeten worden bewaard bij 10 naar 30 °C tenzij anders vermeld, in hun gesloten containers in een droge omgeving. Standaardverpakkingsgrootte is 500 g.
Catalogus nummer: (PRSI91-789)
Leverancier: ProSci Inc.
Omschrijving: Superoxide Dismutase (SOD2) belongs to the iron/manganese superoxide dismutase family. SOD2 is a mitochondrial matrix protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 transforms toxic superoxide, a byproduct of the mitochondrial electron transport chain into hydrogen peroxide and diatomic oxygen. It is reported that oxidative stress plays an essential role in the development of breast cancer, while SOD2 is one of the primary enzymes that directly convert potential harmful oxidizing species to harmless metabolites.
UOM: 1 * 0,05 mg

New Product


Catalogus nummer: (APPC181369.1611)
Leverancier: PanReac AppliChem
Omschrijving: Iron(II) ammonium sulphate can be used for the determination of COD, using ferroin indicator.
UOM: 1 * 1.000 mL

Catalogus nummer: (USBI037118-HRP)
Leverancier: US Biological
Omschrijving: Anti-ISCU Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
UOM: 1 * 200 µl


Catalogus nummer: (ROTH4463.1)
Leverancier: Roth Carl
Omschrijving: Iron(III) oxide
UOM: 1 * 250 g

Market Source Item This is a MarketSource item. Additional charges may apply

Leverancier: VWR Chemicals
Omschrijving: Niet-toxische drogers voor absorptie van vloeistof in de atmosfeer en gasstromen met ijzerzouten als kleurindicator. Het droge materiaal heeft een feloranje kleur en verandert bij absorptie van water naar bleekbeige/wit.
Catalogus nummer: (HECH51071012)
Leverancier: GLASWARENFABRIK KARL HECHT
Omschrijving: These gauzes are made of galvanised iron wire and feature a ceramic centre.
UOM: 1 * 1 ST


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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