U heeft gezocht op: Iron+disilicide

Catalogus nummer: (BOSSBS-8338R-A680)

Leverancier: Bioss

Omschrijving: Defects in PANK2 are the cause of neurodegeneration with brain iron accumulation type 1 (NBIA1); also known as pantothenate kinase-associated neurodegeneration (PKAN) or Hallervorden-Spatz syndrome (HSS). It is an autosomal recessive neurodegenerative disorder associated with iron accumulation in the brain, primarily in the basal ganglia. Clinical manifestations include progressive muscle spasticity, hyperreflexia, muscle rigidity, dystonia, dysarthria, and intellectual deterioration which progresses to severe dementia over several years. It is clinically classified into classic, atypical, and intermediate phenotypes. Classic forms present with onset in the first decade, rapid progression, loss of independent ambulation within 15 years. Atypical forms have onset in the second decade, slow progression, maintenance of independent ambulation up to 40 years later. Intermediate forms manifest onset in the first decade with slow progression or onset in the second decade with rapid progression. Patients with early onset tend to also develop pigmentary retinopathy, whereas those with later onset tend to also have speech disorders and psychiatric features. All patients have the 'eye of the tiger' sign on brain MRI.Defects in PANK2 are the cause of hypoprebetalipoproteinemia, acanthocytosis, retinitis pigmentosa, and pallidal degeneration (HARP). HARP is a rare syndrome with many clinical similarities to NBIA1.

UOM: 1 * 100 µl

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Leverancier: Honeywell Chemicals

Omschrijving: Iron(III) sulphate hydrate 21-23% (Fe basis), Puriss. p.a., Fluka™

MSDS

Leverancier: Hach

Omschrijving: For accuracy checks in iron determinations.

Certificaten

Leverancier: MP Biomedicals

Omschrijving: Ferrous ammonium sulphate is often employed as an analytical standard, and has been used in a variety of other applications from nanomaterials to general redox reactions. It is used for titration purposes.

Leverancier: LGC Standards PROMOCHEM

Omschrijving: This reference standard is intended for use in checking chemical methods of analysis and in the calibration with instrumental methods of analysis.

Catalogus nummer: (PROONIST-3126A)

Leverancier: LGC Standards PROMOCHEM

Omschrijving: This standard reference material is intended for use as a primary calibration standard for the quantitative determination of iron.

UOM: 1 * 50 mL

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Leverancier: Honeywell Chemicals

Omschrijving: Ammonium iron(II) sulphate hexahydrate ≥99.0% (RT), Puriss. p.a. ISO, Reag. Ph. Eur., Fluka™

Leverancier: Biowest

Omschrijving: Calf serum is the liquid fraction of whole blood that is collected after the blood is allowed to clot; it is the blood plasma with the fibrinogens removed. Serum includes all proteins not used in blood clotting (coagulation) and all the electrolytes, antibodies, antigens, hormones, and any exogenous substances. Calf serum is used as a blocking agent in immunoassays and controls.

Leverancier: Honeywell Chemicals

Omschrijving: Iron(II) chloride tetrahydrate ≥99.0% (RT), Puriss. p.a., Fluka™

MSDS

Leverancier: USBECK Laborgeräte

Omschrijving: Vernikkeld messing met gietijzeren voet.

Catalogus nummer: (BOSSBS-9521R-CY5)

Leverancier: Bioss

Omschrijving: Ferrochelatase catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway, and is localised in the mitochondrion. Defects in ferrochelatase are associated with protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. Porphyrias are a group of inherited or acquired disorders of certain enzymes in the heme biosynthetic pathway (also called porphyrin pathway). They are broadly classified as hepatic porphyrias or erythropoietic porphyrias, based on the site of the overproduction and mainly accumulation of the porphyrins (or their chemical precursors). They manifest with either skin problems, or neurological complications, or occasionally both.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-9521R-CY3)

Leverancier: Bioss

Omschrijving: Ferrochelatase catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway, and is localised in the mitochondrion. Defects in ferrochelatase are associated with protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. Porphyrias are a group of inherited or acquired disorders of certain enzymes in the heme biosynthetic pathway (also called porphyrin pathway). They are broadly classified as hepatic porphyrias or erythropoietic porphyrias, based on the site of the overproduction and mainly accumulation of the porphyrins (or their chemical precursors). They manifest with either skin problems, or neurological complications, or occasionally both.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-9521R-A555)

Leverancier: Bioss

Omschrijving: Ferrochelatase catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway, and is localised in the mitochondrion. Defects in ferrochelatase are associated with protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. Porphyrias are a group of inherited or acquired disorders of certain enzymes in the heme biosynthetic pathway (also called porphyrin pathway). They are broadly classified as hepatic porphyrias or erythropoietic porphyrias, based on the site of the overproduction and mainly accumulation of the porphyrins (or their chemical precursors). They manifest with either skin problems, or neurological complications, or occasionally both.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-5810R-CY3)

Leverancier: Bioss

Omschrijving: Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration.Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors.The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.

UOM: 1 * 100 µl

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Catalogus nummer: (ACSD1037801)

Leverancier: CPACHEM

Omschrijving: Ferric chloride solution Reag. Ph. Eur. R1

UOM: 1 * 1.000 mL

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Catalogus nummer: (BOSSBS-15472R-A647)

Leverancier: Bioss

Omschrijving: HGD is a 445 amino acid protein that belongs to the homogentisate dioxygenase family and is involved in the pathway of amino acid degradation. Expressed at high levels in kidney, colon, liver, prostate and small intestine, HGD uses iron as a cofactor to catalyse the oxygen-dependent conversion of homogentisate to 4-maleylacetoacetate, a reaction that is the fourth step in the creation of L-phenylalanine from fumarate and acetoacetic acid. Defects in the gene encoding HGD are the cause of alkaptonuria (AKU), an autosomal recessive disorder that is characterised by urine that turns dark on standing and alkalinisation, black ochronotic pigmentation of cartilage and collagenous tissues and spine arthritis.

UOM: 1 * 100 µl

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