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Image Unavailable-BOSSBS-13182R-HRP

Anti-FLNC Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalogus nummer: (BOSSBS-13182R-HRP)
Leverancier: Bioss
Omschrijving: Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross-linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13182R-CY7

Anti-FLNC Rabbit Polyclonal Antibody (Cy7®)

Catalogus nummer: (BOSSBS-13182R-CY7)
Leverancier: Bioss
Omschrijving: Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross-linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13182R-FITC

Anti-FLNC Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalogus nummer: (BOSSBS-13182R-FITC)
Leverancier: Bioss
Omschrijving: Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross-linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-13182R-A647

Anti-FLNC Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalogus nummer: (BOSSBS-13182R-A647)
Leverancier: Bioss
Omschrijving: Muscle-specific filamin, which plays a central role in muscle cells, probably by functioning as a large actin-cross-linking protein. May be involved in reorganizing the actin cytoskeleton in response to signaling events, and may also display structural functions at the Z lines in muscle cells. Critical for normal myogenesis and for maintaining the structural integrity of the muscle fibers.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6558R-A750

Anti-OLFM4 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalogus nummer: (BOSSBS-6558R-A750)
Leverancier: Bioss
Omschrijving: May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin.
UOM: 1 * 100 µl
Image Unavailable-903-0426

VWR®, Hitachi ChromasterUltra RS Opties voor Hoofdmodules voor UHPLC-systemen

Catalogus nummer: (903-0426)
Leverancier: VWR Collection
Omschrijving: ChromasterUltra Rs, ChromasterUltra Rs USB-AID, d-line cable (0,5 m)
UOM: 1 * 1 ST
Image Unavailable-BOSSBS-9298R-CY3

Anti-BCL7B Rabbit Polyclonal Antibody (Cy3®)

Catalogus nummer: (BOSSBS-9298R-CY3)
Leverancier: Bioss
Omschrijving: BCL7B shows high homology to the BCL7A protein, which is known to be directly involved in a complex chromosomal translocation in Burkitt lymphoma cell lines. The specific function of BCL7B has not yet been determined. However, it may play a role in lung tumor development or progression. The BCL7B gene is located at a chromosomal region commonly deleted in the congenital disorder, Williams syndrome.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-6079R-HRP

Anti-NPRL2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalogus nummer: (BOSSBS-6079R-HRP)
Leverancier: Bioss
Omschrijving: NPR2L is homologous to yeast nitrogen permease and is a candidate tumor suppressor, being a negative regulator of cell cycle. Most abundant in skeletal muscle, followed by brain, liver, and pancreas, with lower amounts in lung, kidney, placenta, and heart. Expressed in most lung cancer cell lines tested. There are two isoforms, produced by alternative splicing.
UOM: 1 * 100 µl
Product Image-BOSSBS-6742R

Anti-Prostate and colon associated protein Rabbit Polyclonal Antibody

Catalogus nummer: (BOSSBS-6742R)
Leverancier: Bioss
Omschrijving: Isoform 2 is expressed in colon, breast, prostate, pancreas and kidney tumor cell lines. Isoform 2 is expressed at high levels in kidney, prostate, brain, small intestine and pancreas, at moderate levels in placenta and colon, at low levels in lung, liver and heart, and at very low levels in spleen, thymus, peripheral mononuclear blood cells, testis and ovary.
UOM: 1 * 100 µl
Image Unavailable-PRSI33-473

Anti-TNF Mouse Monoclonal Antibody [clone: J2D10]

Catalogus nummer: (PRSI33-473)
Leverancier: ProSci Inc.
Omschrijving: This antibody neutralises human TNFa mediated cytotoxicity of L929 cells and inhibits tumour growth in mice. It protects mice against toxicity of hTNFa. Tumor Necrosis Factor Alpha (TNF alpha) is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha is believed to mediate pathogenic shock and tissue injury associated with endotoxemia. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17 kDa band following SDS PAGE under non-reducing conditions. TNF alpha is closely related to the 25 kDa protein Tumor Necrosis Factor beta (lymphotoxin), sharing the same receptors and cellular actions. TNF alpha causes cytolysis of certain transformed cells, being synergistic with interferon gamma in its cytotoxicity. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production.
UOM: 1 * 1 EA

New Product


Product Image-PRSI30-283

Anti-FBXW7 Rabbit Polyclonal Antibody

Catalogus nummer: (PRSI30-283)
Leverancier: ProSci Inc.
Omschrijving: FBXW7 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. This protein binds directly to cyclin E and probably targets cyclin E for ubiquitin-mediated degradation. Mutations in FBXW7 gene are detected in ovarian and breast cancer cell lines, implicating the gene's potential role in the pathogenesis of human cancers.This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene was previously referred to as FBX30, and belongs to the Fbws class; in addition to an F-box, this protein contains 7 tandem WD40 repeats. This protein binds directly to cyclin E and probably targets cyclin E for ubiquitin-mediated degradation. Mutations in this gene are detected in ovarian and breast cancer cell lines, implicating the gene's potential role in the pathogenesis of human cancers. Three transcript variants encoding three different isoforms have been found for this gene.
UOM: 1 * 1 EA
Image Unavailable-BOSSBS-6114R-CY5

Anti-TUSC1 Rabbit Polyclonal Antibody (Cy5®)

Catalogus nummer: (BOSSBS-6114R-CY5)
Leverancier: Bioss
Omschrijving: This gene is located within the region of chromosome 9p that harbors tumor suppressor genes critical in carcinogenesis. It is an intronless gene which is downregulated in non-small-cell lung cancer and small-cell lung cancer cell lines, suggesting that it may play a role in lung tumorigenesis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11462R-A750

Anti-BCAS1/NABC1 Rabbit Polyclonal Antibody (Alexa Fluor® 750)

Catalogus nummer: (BOSSBS-11462R-A750)
Leverancier: Bioss
Omschrijving: NaBC1 is a protein found amplified in most breast carcinoma forms. It is expressed primarily as a cytoplasmic, detergent-stable homodimer that has a tendency to interact with DYNLL1 (PIN) and DYNLL2. Breast tumour lines that exhibit 20q13.2 gene amplification express much higher levels of the protein as compared to the levels found in other breast cancer lines that do not overexpress the NaBC1 mRNA. However, this upregulation does not affect growth rate or anchoring abilities of a cell, indicating the oncogenic properties of NaBC1 differ from that of other oncogenes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2539R-CY5.5

Anti-TRIM63 Rabbit Polyclonal Antibody (Cy5.5®)

Catalogus nummer: (BOSSBS-2539R-CY5.5)
Leverancier: Bioss
Omschrijving: This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle. [provided by RefSeq].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2539R-CY7

Anti-TRIM63 Rabbit Polyclonal Antibody (Cy7®)

Catalogus nummer: (BOSSBS-2539R-CY7)
Leverancier: Bioss
Omschrijving: This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is localized to the Z-line and M-line lattices of myofibrils, where titin's N-terminal and C-terminal regions respectively bind to the sarcomere. In vitro binding studies have shown that this protein also binds directly to titin near the region of titin containing kinase activity. Another member of this protein family binds to microtubules. Since these family members can form heterodimers, this suggests that these proteins may serve as a link between titin kinase and microtubule-dependent signal pathways in muscle. [provided by RefSeq].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-12303R

Anti-EDAG Rabbit Polyclonal Antibody

Catalogus nummer: (BOSSBS-12303R)
Leverancier: Bioss
Omschrijving: Hemogen is a 484 amino acid protein encoded by the human gene HEMGN. Hemogen is a nuclear protein that is expressed in hematopoietic precursor cells and can be detected in CD34+ and K-562 leukemia cell line. It is also expressed in bone marrow, testis, thymus and thyroid tumors, non-Hodgkin lymphoma, various leukemia cell lines, peripheral blood mononuclear cells (PBMCs) and bone marrow mononuclear cells (BMMCs) of patients with leukemia. Hemogen is down-regulated during megakaryocytic differentiation of K-562 cells by 12-O-tetradecanoylphorbol-13-acetate (TPA) (at protein level). It can be up-regulated in normal PBMCs by mitogens.
UOM: 1 * 100 µl
Bel voor prijs
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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