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Anti-MET Rabbit Polyclonal Antibody (Cy5®)

Catalogus nummer: (BOSSBS-1733R-CY5)

Leverancier: Bioss

Omschrijving: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects. During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation. In adults, participates in wound healing as well as organ regeneration and tissue remodeling. Promotes also differentiation and proliferation of hematopoietic cells. Acts as a receptor for Listeria internalin inlB, mediating entry of the pathogen into cells.

UOM: 1 * 100 µl

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Anti-MET Rabbit Polyclonal Antibody (Cy5.5®)

Catalogus nummer: (BOSSBS-0668R-CY5.5)

Leverancier: Bioss

UOM: 1 * 100 µl

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Anti-MET Rabbit Polyclonal Antibody (APC (Allophycocyanin))

Catalogus nummer: (USBIM3007-13L-APC)

Leverancier: US Biological

Omschrijving: Anti-MET Rabbit Polyclonal Antibody (APC (Allophycocyanin))

UOM: 1 * 200 µl

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Anti-p-MET Rabbit Polyclonal Antibody [clone: Y1235]

Catalogus nummer: (BWRLBS64017)

Leverancier: Bioworld Technology

Omschrijving: A synthetic peptide corresponding to residues in Human MET around the phosphorylation site of Tyrosine 1235.

UOM: 1 * 1 EA

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N-Carbobenzoxy-L-methionine ≥98.0% (by titrimetric analysis)

Leverancier: TCI

Omschrijving: N-Carbobenzoxy-L-methionine ≥98.0% (by titrimetric analysis)

Anti-MET Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

Catalogus nummer: (USBI038367-HRP)

Leverancier: US Biological

Omschrijving: Anti-MET Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))

UOM: 1 * 200 µl

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Anti-Met (c-Met) Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalogus nummer: (BOSSBS-0668R-A680)

Leverancier: Bioss

Omschrijving: Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of these downstream effectors by MET leads to the activation of several signaling cascades including the RAS-ERK, PI3 kinase-AKT, or PLCgamma-PKC. The RAS-ERK activation is associated with the morphogenetic effects while PI3K/AKT coordinates prosurvival effects. During embryonic development, MET signaling plays a role in gastrulation, development and migration of muscles and neuronal precursors, angiogenesis and kidney formation. In adults, participates in wound healing as well as organ regeneration and tissue remodelling. Promotes also differentiation and proliferation of hematopoietic cells. Acts as a receptor for Listeria internalin inlB, mediating entry of the pathogen into cells.

UOM: 1 * 100 µl

Sale