U heeft gezocht op: Phorbol

Leverancier: Apollo Scientific

Omschrijving: Unsubstituted parent diterpene from which phorbol esters are derived; biologically inactive in most assays

Catalogus nummer: (ENZOBMLPE1350005)

Leverancier: ENZO LIFE SCIENCES

Omschrijving: Widely used PKC activator (10 to 100 ng/ml).

UOM: 1 * 5 mg

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Leverancier: ENZO LIFE SCIENCES

Omschrijving: PKC activator (10 to 100 ng/ml).

Leverancier: Apollo Scientific

Omschrijving: Widely used PKC activator; less potent than PMA, but also less hydrophobic, making it easier to wash out of cells in tissue culture.

Leverancier: Apollo Scientific

Omschrijving: This is the most commonly used phorbol ester.  It binds to and activates protein kinase C, causes an extremely wide range of effects in cells and tissues, and is a very potent mouse skin tumor promoter. Crit. Rev. Toxicol. 8:  153-197 (1980)

Leverancier: Thermo Fisher Scientific

Omschrijving: CAS No.: 16561-29-8

MSDS

Catalogus nummer: (ENZOALX445047M005)

Leverancier: ENZO LIFE SCIENCES

Omschrijving: Sapintoxin D act as a PKC ligand. Fluorescent, highly potent phorbol ester.

UOM: 1 * 5 mg

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Catalogus nummer: (TNB-4975-UL100)

Leverancier: Tonbo Biosciences

Omschrijving: Cell stimulation cocktail is a ready to use cocktail that can be used for polyclonal cell activation. It is composed of the phorbol ester, PMA (phorbol 12-Myristate 13-Acetate), a calcium ionophore (Ionomycin), and the protein transport inhibitors Brefeldin A and Monensin. It can be used to elicit cytokine production and retention in a variety of cell types allowing for detection of intracellular protein by flow cytometry.

UOM: 1 * 100 µl

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Catalogus nummer: (ENZOALX350089KI225)

Leverancier: ENZO LIFE SCIENCES

Omschrijving: Natural source of phorbol and phorbol esters.

UOM: 1 * 2,25 kg

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Catalogus nummer: (BOSSBS-6425R-A488)

Leverancier: Bioss

Omschrijving: Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-6425R-CY5)

Leverancier: Bioss

Omschrijving: Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-6425R-CY5.5)

Leverancier: Bioss

Omschrijving: Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.

UOM: 1 * 100 µl

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Catalogus nummer: (BOSSBS-6425R-CY7)

Leverancier: Bioss

Omschrijving: Non-selective calcium permeant cation channel probably involved in osmotic sensitivity and mechanosensitivity. Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification. Also activated by low pH, citrate and phorbol esters. Increase of intracellular Ca(2+) potentiates currents. Channel activity seems to be regulated by a calmodulin-dependent mechanism with a negative feedback mechanism. Promotes cell-cell junction formation in skin keratinocytes and plays an important role in the formation and/or maintenance of functional intercellular barriers. Acts as a regulator of intracellular Ca(2+) in synoviocytes. Plays an obligatory role as a molecular component in the nonselective cation channel activation induced by 4-alpha-phorbol 12,13-didecanoate and hypotonic stimulation in synoviocytes and also regulates production of IL-8.

UOM: 1 * 100 µl

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Catalogus nummer: (ENZOBMLPE1860001)

Leverancier: ENZO LIFE SCIENCES

Omschrijving: Ingenol is a diterpenoid related to phorbol. Activates protein kinase C (PKC) and competes with [3H]phorbol dibutyrate for binding to PKCα (Ki for binding=240 nM). Induces apoptosis. Anticancer agent. Shows potent antileukemic activity in the P388 mouse assay.

UOM: 1 * 1 mg

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Leverancier: ENZO LIFE SCIENCES

Omschrijving: Selective inhibitor of phosphatidylcholine-specific phospholipase C (PC-PLC). Has been used to study the coupling of phosphatidylcholine-specific phospholipase C with sphingomyelinase. Shows antitumor and antiviral activity. Inhibits basement membrane collagen synthesis, which is the last step in the development of a new blood vessel. Inhibits induction of nitric oxide synthases (NOS). Induces apoptosis. It indirectly inhibits phorbol ester stimulated PLD activity.

Catalogus nummer: (BOSSBS-1477R)

Leverancier: Bioss

Omschrijving: human homolog binds ADP-ribosylation factor (ARF) and inhibits ARF dependent phorbol ester induced secretion of matrix metalloproteinase 9 [RGD]

UOM: 1 * 100 µl

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