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Image Unavailable-BOSSBS-5337R-CY7

Anti-EIF4EBP1 Rabbit Polyclonal Antibody (Cy7®)

Catalogus nummer: (BOSSBS-5337R-CY7)
Leverancier: Bioss
Omschrijving: Regulates eIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1329R-FITC

Anti-ZO1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalogus nummer: (BOSSBS-1329R-FITC)
Leverancier: Bioss
Omschrijving: The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1329R-A647

Anti-ZO1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalogus nummer: (BOSSBS-1329R-A647)
Leverancier: Bioss
Omschrijving: The N-terminal may be involved in transducing a signal required for tight junction assembly, while the C-terminal may have specific properties of tight junctions. The alpha domain might be involved in stabilizing junctions. Plays a role in the regulation of cell migration by targeting CDC42BPB to the leading edge of migrating cells.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0127M-A750

Anti-Bax Mouse Polyclonal Antibody (Alexa Fluor® 750)

Catalogus nummer: (BOSSBS-0127M-A750)
Leverancier: Bioss
Omschrijving: Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-4308R-FITC

Anti-ERN1 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))

Catalogus nummer: (BOSSBS-4308R-FITC)
Leverancier: Bioss
Omschrijving: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8680R-A750

Anti-IRE1a Rabbit Polyclonal Antibody (ALEXA FLUOR® 750)

Catalogus nummer: (BOSSBS-8680R-A750)
Leverancier: Bioss
Omschrijving: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-8680R-CY7

Anti-IRE1a Rabbit Polyclonal Antibody (Cy7®)

Catalogus nummer: (BOSSBS-8680R-CY7)
Leverancier: Bioss
Omschrijving: Senses unfolded proteins in the lumen of the endoplasmic reticulum via its N-terminal domain which leads to enzyme auto-activation. The active endoribonuclease domain splices XBP1 mRNA to generate a new C-terminus, converting it into a potent unfolded-protein response transcriptional activator and triggering growth arrest and apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0653R-A647

Anti-DMT1 Rabbit Polyclonal Antibody (Alexa Fluor® 647)

Catalogus nummer: (BOSSBS-0653R-A647)
Leverancier: Bioss
Omschrijving: Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-0653R-A680

Anti-Dmt1 Rabbit Polyclonal Antibody (Alexa Fluor® 680)

Catalogus nummer: (BOSSBS-0653R-A680)
Leverancier: Bioss
Omschrijving: Important in metal transport, in particular iron. Can also transport manganese, cobalt, cadmium, nickel, vanadium and lead. Involved in apical iron uptake into duodenal enterocytes.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2201R-CY5

Anti-ARHGEF2 Rabbit Polyclonal Antibody (Cy5®)

Catalogus nummer: (BOSSBS-2201R-CY5)
Leverancier: Bioss
Omschrijving: GEF-H1 is a Rho guanine nucleotide exchange factor that localizes to microtubules and regulates Rho activity in response to microtubule destabilization (loss of interaction between GEF-H1 and microtubules leads to activation of Rho). This protein has also been shown to localize to tight junctions and modulate polarized cell permeability.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-3445R-CY7

Anti-THR927 Rabbit Polyclonal Antibody (Cy7®)

Catalogus nummer: (BOSSBS-3445R-CY7)
Leverancier: Bioss
Omschrijving: Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq].
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-7113R-CY5.5

Anti-FEM1B Rabbit Polyclonal Antibody (Cy5.5®)

Catalogus nummer: (BOSSBS-7113R-CY5.5)
Leverancier: Bioss
Omschrijving: Component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit. Involved in apoptosis by acting as a death receptor-associated protein that mediates apoptosis. Also involved in glucose homeostasis in pancreatic islet. Functions as an adapter/mediator in replication stress-induced signaling that leads to the activation of CHEK1.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1858R-CY5.5

Anti-NTN1 Rabbit Polyclonal Antibody (Cy5.5®)

Catalogus nummer: (BOSSBS-1858R-CY5.5)
Leverancier: Bioss
Omschrijving: Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-1858R-CY5

Anti-NTN1 Rabbit Polyclonal Antibody (Cy5®)

Catalogus nummer: (BOSSBS-1858R-CY5)
Leverancier: Bioss
Omschrijving: Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-11696R-A350

Anti-HAP40/F8a Rabbit Polyclonal Antibody (Alexa Fluor® 350)

Catalogus nummer: (BOSSBS-11696R-A350)
Leverancier: Bioss
Omschrijving: The Huntingtin protein contains a polyglutamine region, which leads to Huntingtin’s disease (HD) when the number of glutamine repeats exceeds thirty-five. The mutated Huntingtin protein acts within the nucleus to induce neurodegeneration by a cell-specific apoptotic mechanism. The loss of activity of the Huntingtin protein may be contributed to abnormal interactions between the mutant protein and other associated cellular proteins. Huntingtin interacts with a variety of proteins including HAP1, glyceraldehyde phosphate dehydrogenase (GAPDH), HAP40, Rab5 and HIP1. HAP40 mediates the recruitment of Huntingtin by Rab5 onto early endosomes. Specifically, this complex regulates endosome motility, which may be a key event of the pathogenetic process leading to neurodegeneration in HD.
UOM: 1 * 100 µl
Image Unavailable-BOSSBS-2615R-A488

Anti-IL18R1 Rabbit Polyclonal Antibody (Alexa Fluor® 488)

Catalogus nummer: (BOSSBS-2615R-A488)
Leverancier: Bioss
Omschrijving: Receptor for interleukin 18 (IL-18). Binding to the agonist leads to the activation of NF-kappa-B.
UOM: 1 * 100 µl
Bel voor prijs
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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