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Catalogus nummer: (BOSSBS-13530R)
Leverancier: Bioss
Omschrijving: G protein-coupled receptors (GPCRs), also designated seven transmembrane (7TM) receptors and heptahelical receptors, are a protein family which interacts with G proteins (heterotrimeric GTPases) to synthesize intracellular second messengers such as diacylglycerol, cyclic AMP, inositol phosphates and calcium ions. Their diverse biological functions range from vision and olfaction to neuronal and endocrine signaling, along with involvement in many pathological conditions. GPR31 (G-protein coupled receptor 31) is a 319 amino acid orphan receptor that localizes to the cell membrane. GPR31 shares 25-33% homology with members of the chemokine, purino and somatostatin receptor gene families.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-11332R)
Leverancier: Bioss
Omschrijving: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-11332R-CY3)
Leverancier: Bioss
Omschrijving: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
UOM: 1 * 100 µl


Catalogus nummer: (BSENC-1521-500)
Leverancier: Biosensis
Omschrijving: Rod shaped photoreceptor cells that are required for image-forming vision at low light intensity and for photoreceptor cell viability after birth (ref: SWISSPROT).
UOM: 1 * 500 µl


Leverancier: 3M
Omschrijving: Met een modern, slank ontwerp combineert de bril uit de 2800-serie prestaties, comfort en stijl en biedt de drager een uitstekend gezichtsveld. Verkrijgbaar met PC of acetaat lenzen met of zonder indirecte ventilatie.

Leverancier: VWR Collection
Omschrijving: Deze koudlichtbron met compacte en stabiele aluminium behuizing en temperatuurventilatorregeling zorgt voor een optimale en homogene verlichting van de lichtgeleider. Het is daarom ideaal voor opnames op hoge snelheid in een verscheidenheid aan toepassingen, zoals kwaliteitsborging, industriële endoscopie, machine vision en cleanroomtoepassingen. De helderheid overtreft ruimschoots de helderheid van een conventionele 250 W halogeenlichtbron. Verwachte LED-levensduur van 50.000 uur.

Catalogus nummer: (BOSSBS-11715R-CY3)
Leverancier: Bioss
Omschrijving: CLN8, a 286 amino acid transmembrane protein, localizes mainly to the endoplasmic reticulum, but also partially to the ER-Golgi intermediate compartment (ERGIC). Mutations in the CLN8 gene cause neuronal ceroid lipofuscinosis 8 and progressive epilepsy with mental retardation (EPMR). Both disorders are forms of neuronal ceroid-lipofuscinose (NCL), a group of progressive neurodegenerative diseases found in children, characterized by failure of psychomotor development, impaired vision, seizures and premature death. The CLN8 protein is one of eight proteins in the CLN family, including CLN1-CLN7, which are associated with NCL.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-11715R-FITC)
Leverancier: Bioss
Omschrijving: CLN8, a 286 amino acid transmembrane protein, localizes mainly to the endoplasmic reticulum, but also partially to the ER-Golgi intermediate compartment (ERGIC). Mutations in the CLN8 gene cause neuronal ceroid lipofuscinosis 8 and progressive epilepsy with mental retardation (EPMR). Both disorders are forms of neuronal ceroid-lipofuscinose (NCL), a group of progressive neurodegenerative diseases found in children, characterized by failure of psychomotor development, impaired vision, seizures and premature death. The CLN8 protein is one of eight proteins in the CLN family, including CLN1-CLN7, which are associated with NCL.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-11715R-CY5)
Leverancier: Bioss
Omschrijving: CLN8, a 286 amino acid transmembrane protein, localizes mainly to the endoplasmic reticulum, but also partially to the ER-Golgi intermediate compartment (ERGIC). Mutations in the CLN8 gene cause neuronal ceroid lipofuscinosis 8 and progressive epilepsy with mental retardation (EPMR). Both disorders are forms of neuronal ceroid-lipofuscinose (NCL), a group of progressive neurodegenerative diseases found in children, characterized by failure of psychomotor development, impaired vision, seizures and premature death. The CLN8 protein is one of eight proteins in the CLN family, including CLN1-CLN7, which are associated with NCL.
UOM: 1 * 100 µl


Catalogus nummer: (BOSSBS-11715R-A680)
Leverancier: Bioss
Omschrijving: CLN8, a 286 amino acid transmembrane protein, localizes mainly to the endoplasmic reticulum, but also partially to the ER-Golgi intermediate compartment (ERGIC). Mutations in the CLN8 gene cause neuronal ceroid lipofuscinosis 8 and progressive epilepsy with mental retardation (EPMR). Both disorders are forms of neuronal ceroid-lipofuscinose (NCL), a group of progressive neurodegenerative diseases found in children, characterised by failure of psychomotor development, impaired vision, seizures and premature death. The CLN8 protein is one of eight proteins in the CLN family, including CLN1-CLN7, which are associated with NCL.
UOM: 1 * 100 µl


Catalogus nummer: (111-1844)
Leverancier: VWR Collection
Omschrijving: Uiterst lichte en moderne veiligheidsbril met uitstekend blikveld en uitzonderlijke bescherming.
UOM: 1 * 1 ST


Catalogus nummer: (BOSSBS-11715R-A555)
Leverancier: Bioss
Omschrijving: CLN8, a 286 amino acid transmembrane protein, localizes mainly to the endoplasmic reticulum, but also partially to the ER-Golgi intermediate compartment (ERGIC). Mutations in the CLN8 gene cause neuronal ceroid lipofuscinosis 8 and progressive epilepsy with mental retardation (EPMR). Both disorders are forms of neuronal ceroid-lipofuscinose (NCL), a group of progressive neurodegenerative diseases found in children, characterized by failure of psychomotor development, impaired vision, seizures and premature death. The CLN8 protein is one of eight proteins in the CLN family, including CLN1-CLN7, which are associated with NCL.
UOM: 1 * 100 µl


Leverancier: Apollo Scientific
Omschrijving: Novec HFE-71DA Engineered Fluid (3M)

Catalogus nummer: (MMMASCCS07SGAF-GRN)
Leverancier: 3M
Omschrijving: 3M™ Solus™ CCS Safety Glasses are rimless safety glasses that feature lime green temples with a Corded Control System (CCS) for attaching corded earplugs. The polycarbonate lens features a Scotchgard™ anti-fog and anti-scratch coating on both sides for increased durability and improved vision.
UOM: 1 * 1 ST


Catalogus nummer: (111-1841)
Leverancier: VWR Collection
Omschrijving: Omhullende, moderne ruimzichtbril, speciaal ontworpen voor kleine hoofden, biedt een uitstekend panoramisch zicht. De ruimzichtbril bestaat uit een PC lens, een PVC frame en een polyester/rubberen hoofdband.
UOM: 1 * 1 ST


Catalogus nummer: (BOSSBS-11332R-FITC)
Leverancier: Bioss
Omschrijving: Glutamic acid rich protein (GARP) is a soluble protein localized to the outer segments of the rod photoreceptor. It forms a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. There are 3 isoforms produced by alternative splicing. Isoform GARP2 is a high affinity rod photoreceptor phosphodiesterase (PDE6)-binding protein that modulates its catalytic properties; it is a regulator of spontaneous activation of rod PDE6, thereby serving to lower rod photoreceptor 'dark noise' and allowing these sensory cells to operate at the single photon detection limit. Defects in GARP are the cause of retinitis pigmentosa type 25 (RP25). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.
UOM: 1 * 100 µl


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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
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