U heeft gezocht op: Vitamin+B12+(cyanocobalamin)


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Leverancier: MP Biomedicals
Omschrijving: Preparation Method: MP Intrinsic Factor is produced from the pylorus mucous membrane of the pig, of which only a small part is used. Only the part which, according to histological examinations has proved to have a high content of Intrinsic Factor, is used.
Applications: Intrinsic Factor is used in the treatment not only of classical pernicious anaemia, but also in the treatment of other macrocytic anaemias, where it replaces the Intrinsic Factor which may be lacking in the patient's own gastric juice. In this way Intrinsic Factor is recommended against anaemias that appear 6 to 12 months after serious gastric operations, and against anaemias that are secondary effects of the treatment with certain medicines, e.g. against epilepsy. However, the dietetic use in multi-vitamin preparations is of the greatest importance. In older people there has been observed a degeneration of the gastric mucous membrane, whose secretion of Intrinsic Factor is insufficient to ensure the resorption of the necessary quantity of B-12 from their diet. In order to delay this development it is useful to prescribe a small quantity of Intrinsic Factor with B-12 and other vitamins to these patients.
Product Description: Intrinsic factor is a glucoprotein extracted from the pylorus part of the gastric mucous membrane. Its presence is considered necessary for the absorption of Vitamin B-12.
Unit Definition: The activity is normally indicated in Coli units, the number of which are proportional to the binding power of the substance to Vitamin B-12.

Application Areas: Absorption of vitamin B12
Product Type: Proteins, Enzymes & Peptides
Presentation: Tan Powder
Foreign activity: Salmonella=Negative, E. coli=Negative
NOTES: Standard Plate Count <1000/g
Solubility: Slightly soluble in toluene; practically insoluble in water.
Storage & Handling: -20°C

Catalogus nummer: (PRSI91-248)
Leverancier: ProSci Inc.
Omschrijving: Uroporphyrinogen-III Synthase is an enzyme which belongs to the uroporphyrinogen-III synthase family. Uroporphyrinogen-III Synthase is ubiquitous and it is involved in Porphyrin metabolism. Porphyrins act as cofactors for a multitude of enzymes that perform a variety of processes within the cell such as Methionine synthesis (Vitamin B12) or oxygen transport (Heme). Uroporphyrinogen-III Synthase can catalyze cyclization of the linear Tetrapyrrole, Hydroxymethylbilane, to the Macrocyclic Uroporphyrinogen III, the branch point for the various sub-pathways leading to the wide diversity of Porphyrins. Defects in Uroporphyrinogen-III Synthase are the cause of Congenital Erythropoietic Porphyria (CEP).
UOM: 1 * 1 EA


Catalogus nummer: (PRSI56-874)
Leverancier: ProSci Inc.
Omschrijving: The CD320 antigen gene encodes the transcobalamin receptor (TCBLR). Cellular uptake of cobalamin (vitamin B12) is mediated by receptors expressed on the cell surface. Transcobalamin II (TCN2; MIM 613441), a plasma protein secreted by endothelial cells, binds the cobalamin absorbed in the distal ileum and carries 10 to 30% of total circulating cobalamin. CD320 encodes a transcobalamin receptor that binds TCN2-cobalamin at the plasma membrane and internalizes the complex by endocytosis (Quadros et al., 2009 [PubMed 18779389]).
UOM: 1 * 400 µl

New Product


Leverancier: MP Biomedicals
Omschrijving: Cobalt chloride is utilized in commercial applications such as electroplating, catalyst preparation, painting on glass and porcelain, and in the manufacture of vitamin B12.

Catalogus nummer: (PHR1234-1G)
Leverancier: Merck
Omschrijving: Organic Standard, Cyanocobalamin
UOM: 1 * 1 g

Leverancier: MP Biomedicals
Omschrijving: δ-Aminolevulinic acid hydrochloride is the universal precursor of tetrapyrroles, such as chlorophyll and heme.
δ-Aminolevulinic acid hydrochloride is used in the synthesis of hemes, vitamin B12 and bacteriochlorophyll. It is used in porphyrin biosynthesis studies. It enhances chlorophyll formation and may be used as a photodynamic herbicide is a precursor of tetrapyrroles in the biosynthesis of chlorophyll and heme.
5-Aminolevulinic acid (5-ALA) is an intermediate in heme biosynthesis and is being studied as an inducing reagent for protoporphyrin IX (PPIX) dependent fluorescence diagnosis of metastatic lymph nodes. 5-ALA is used for photodynamic therapy of diseases such as Paget’s disease and HPV infection-associated cervical condylomata acuminata.

Catalogus nummer: (1152011.)
Leverancier: USP
Omschrijving: USP Reference Standards are specified for use in conducting official USP–NF tests and assays. USP also provides Reference Standards specified in the Food Chemicals Codex as well as authentic substances—high-quality chemical samples—as a service to analytical, clinical, pharmaceutical and research laboratories. To confirm accuracy and reproducibility, USP Reference Standards are rigorously tested and evaluated by multiple independent laboratories including USP, commercial, regulatory, and academic labs. USP also provide publicly available, official documentary standards for pharmaceutical ingredients in the USP–NF that link directly with our primary reference standards.
UOM: 1 * 300 mg


Leverancier: Thermo Fisher Scientific
Omschrijving: Coenzyme B12

Catalogus nummer: (ABCAAB91364-50)
Leverancier: Abcam
Omschrijving: Anti-Mouse Mouse 0 Antibody [clone: B12/8] (APC)
UOM: 1 * 1 EA


Leverancier: Abcam
Omschrijving: Anti-STAT3 (phospho Y705) Rabbit Monoclonal Antibody [clone: Stat3Y705-B12]

Catalogus nummer: (ABCAAB7027-100)
Leverancier: Abcam
Omschrijving: Anti-PRMT1 Mouse Monoclonal Antibody [clone: MAT-B12]
UOM: 1 * 1 EA


Leverancier: Abcam
Omschrijving: Anti-STAT3 (phospho Y705) Rabbit Monoclonal Antibody [clone: Stat3Y705-B12] (PE)

Leverancier: Abcam
Omschrijving: Anti-STAT3 (phospho Y705) Rabbit Monoclonal Antibody [clone: Stat3Y705-B12] (APC)

Catalogus nummer: (ABCAAB91361-100)
Leverancier: Abcam
Omschrijving: Anti-Mouse Mouse 0 Antibody [clone: B12/8]
UOM: 1 * 1 EA


Catalogus nummer: (ABCAAB91363-50)
Leverancier: Abcam
Omschrijving: Anti-Mouse Mouse 0 Antibody [clone: B12/8] (PE)
UOM: 1 * 1 EA


Leverancier: Abcam
Omschrijving: Anti-STAT3 (phospho Y705) Rabbit Monoclonal Antibody [clone: Stat3Y705-B12] (FITC)

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Stock for this item is limited, but may be available in a warehouse close to you. Please make sure that you are logged in to the site so that available stock can be displayed. If the call is still displayed and you need assistance, please call us at 1-800-932-5000.
This product is marked as restricted and can only be purchased by approved Shipping Accounts. If you need further assistance, email VWR Regulatory Department at Regulatory_Affairs@vwr.com
-Additional Documentation May be needed to purchase this item. A VWR representative will contact you if needed.
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